Results 141 to 150 of about 2,911,926 (286)

Thermally Reconfigurable Interfaces Engineered by Robust Ionogels for Intelligent TENG Signal Modulation. [PDF]

Small
Hou J, Ma H, Wang X, Sun P, Wang F.
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Communication Signal Modulation Recognition Method Based on Multi-Feature Multi-Channel ResNet and BiLSTM Neural Network. [PDF]

Sensors (Basel)
Li X, Geng X, Xu Y, Cao F.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

A Broad-Band Self-Powered Photodetector Based on a MoTe₂/Bi₂Te₃ Heterojunction for Optical Imaging and Bias-Controlled Signal Modulation. [PDF]

Materials (Basel)
Du S, Li K, Li W, Feng J, Sheng Y, Tao L, Zheng Z, Song W, Zhao Y.   +8 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

GD2 is a Crucial Ganglioside in the Signal Modulation and Application as a Target of Cancer Therapeutics. [PDF]

Cancer Sci
Furukawa K, Ohmi Y, Hamamura K, Ohkawa Y, Hashimoto N, Tajima O, Kaneko K, Furukawa K.   +7 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Radio Signal Modulation Recognition Method Based on Hybrid Feature and Ensemble Learning: For Radar and Jamming Signals. [PDF]

Sensors (Basel)
Zhou Y, Cao R, Zhang A, Li P.
europepmc   +1 more source

Multifocal Signal Modulation Therapy by Celecoxib: A Strategy for Managing Castration-Resistant Prostate Cancer. [PDF]

Int J Mol Sci, 2019
Benelli R, Barboro P, Costa D, Astigiano S, Barbieri O, Capaia M, Poggi A, Ferrari N.   +7 more
europepmc   +1 more source