Results 61 to 70 of about 2,911,926 (286)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Nonlinearity and Noise Effects in Multi-level Signal Millimeter-Wave over Fiber Transmission using Single- and Dual-Wavelength Modulation [PDF]

, 2010
We transmit multilevel quadrature amplitude modulation (QAM) data-IEEE 802.16 schemes-at 20 MSps and an orthogonal frequency-division multiplexing (OFDM) 802.11 g signal (54 Mbps) with a 25 GHz millimeter-wave over fiber system, which employs a dual ...
Jeanne James, James, Jeanne, Anthony Nkansah, Shen, Pengbo, Xing Liang, Pengbo Shen, Nkansah, Anthony, Gomes, Nathan J., Liang, Xing, Nathan J. Gomes   +9 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Review for wireless communication technology based on digital encoding metasurfaces

Opto-Electronic Advances
Metasurfaces offer exceptional capabilities for controlling electromagnetic waves, enabling the realization of unique electromagnetic properties. As communication technology continues to evolve, metasurfaces present promising applications in wireless ...
Haojie Zhan, Manna Gu, Ying Tian, Huizhen Feng, Mingmin Zhu, Haomiao Zhou, Yongxing Jin, Ying Tang, Chenxia Li, Bo Fang, Zhi Hong, Xufeng Jing, Le Wang   +12 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

NEW METHOD OF GENERATING OF THE PHASE MODULATED SIGNALS

Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019
The new effective method of generating of signals of phase modulation (PM), providing almost limiting linearity of a static modulation characteristic is developed. The structure of the device implementing the offered method is synthesized.
V. A. Ilyinkov, Y. M. Yarkov, A. V. Ilyinkova   +2 more
doaj  

Experimental investigation on the spray characteristics of agricultural full-cone pressure swirl nozzle

Nano Research
We successfully constructed phase-change quantum dots string (PCQDS) systems and studied their signal responses. The PCQDS actually is a cascaded structure consisted of several stochastic resonance (SR) two-state systems, in which inherent non-linearity,
Qin Wan, Fei Zeng, Ziao Lu, Junwei Yu, Feng Pan   +4 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source