Results 11 to 20 of about 3,392,560 (298)
SPdb – a signal peptide database [PDF]
BMC Bioinformatics, 2005 Background The signal peptide plays an important role in protein targeting and protein translocation in both prokaryotic and eukaryotic cells. This transient, short peptide sequence functions like a postal address on an envelope by targeting proteins for
Tan Tin, Choo Khar, Ranganathan Shoba
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Flanking signal and mature peptide residues influence signal peptide cleavage [PDF]
BMC Bioinformatics, 2008 Background Signal peptides (SPs) mediate the targeting of secretory precursor proteins to the correct subcellular compartments in prokaryotes and eukaryotes.
Ranganathan Shoba, Choo Khar
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Recognition of a signal peptide by the signal recognition particle [PDF]
Nature, 2010 Targeting of proteins to appropriate subcellular compartments is a crucial process in all living cells. Secretory and membrane proteins usually contain an amino-terminal signal peptide, which is recognized by the signal recognition particle (SRP) when nascent polypeptide chains emerge from the ribosome.
Janda, C +5 more
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Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization [PDF]
IUCrJ, 2016 Bacterial type I signal peptidases (SPases) are membrane-anchored serine proteases that process the signal peptides of proteins exported via the Sec and Tat secretion systems.
Yi Tian Ting +5 more
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Structure and topology around the cleavage site regulate post-translational cleavage of the HIV-1 gp160 signal peptide [PDF]
eLife, 2017 Like all other secretory proteins, the HIV-1 envelope glycoprotein gp160 is targeted to the endoplasmic reticulum (ER) by its signal peptide during synthesis.
Erik Lee Snapp +10 more
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A novel two-component signal transduction system in propionibacterium acnes and its association with a putative extracellular signalling peptide [PDF]
, 2011 Propionibacterium acnes, a resident micro-organism of human skin, is thought to be involved in the development of inflammatory acne, which is an exclusive human disease affecting more than 80% of the whole population. Quorum sensing is the regulation of
Guan, Shuang
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European Journal of Cell Biology, 2010 N-terminal signal sequences mediate nascent protein targeting to and protein insertion into the membrane of the endoplasmic reticulum. They are typically 15-30 amino acid residues long with a core hydrophobic region flanked by an N-terminal (n-) and a C-terminal region.
Kilic, A. +4 more
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Journal of Diabetes Research, 2003 For years an assumption was made that C‐peptide, a byproduct of insulin biosynthesis, possessed no appreciable physiologic role. As other contributions in this volume amply testify, the time has come to re‐evaluate that notion. C‐peptide either directly through interaction with its specific cell‐surface receptor or indirectly through an interaction ...
Grunberger, George, Sima, Anders A. F.
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Peptide Signaling in the Staphylococci [PDF]
Chemical Reviews, 2010 Gram-negative and Gram-positive bacteria have evolved elaborate machinery to biosynthesize and respond to diverse small-molecule signals. As bacteria grow, these signals accumulate in the extracellular environment until a particular concentration is reached, usually at a specific cell density or “quorum”, activating a regulatory cascade that controls ...
Matthew, Thoendel +3 more
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Signaling Peptides in Plants [PDF]
Cell & Developmental Biology, 2014 In multicellular organisms, growth and development need to be precisely coordinated and are strongly relying on positional information. Positional control is achieved through exchanges of molecular messages between cells and tissues by means of cell-to-cell communication mechanisms.
Ghorbani, Sarieh +3 more
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