Results 121 to 130 of about 98,464 (271)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

An Efficient Image Denoising Approach Using FPGA Type of PYNQ-Z2

Al-Kitab Journal for Pure Sciences
Image denoising techniques have become crucial for computer-assisted analysis due to the increasing number of digital images captured in unfavorable conditions.
Wesam Hujab Saood, Khamees Khalaf Hasan
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Application of signal processing to respiratory cycle related EEG change (RCREC) in children [PDF]

, 2014
Sleep is an important part of everyday life. It directly affects daytime cognition and general performance. In children, sleep is a crucial requirement for growth and learning and lack of sleep may manifest itself as a long lasting developmental deficit.
Motamedi Fakhr, Shayan
core  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Computational Tonality Estimation: Signal Processing and Hidden Markov Models [PDF]

, 2009
PhDThis thesis investigates computational musical tonality estimation from an audio signal. We present a hidden Markov model (HMM) in which relationships between chords and keys are expressed as probabilities of emitting observable chords from a hidden
Noland, Katy C
core  

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A conditional generative adversarial networks and Yolov5 Darknet -based skin lesion localization and classification using independent component analysis model

Informatics in Medicine Unlocked
Automated diagnosis systems significantly improve the early detection of skin cancer, thereby contributing to its successful treatment. Skin lesion segmentation represents a crucial yet challenging issue within the realm of computer-assisted dermoscopy ...
Shweta Koparde, Jameer Kotwal, Swapnil Deshmukh, Sharad Adsure, Poonam Chaudhari, Vinod Kimbahune   +5 more
doaj   +1 more source