Results 101 to 110 of about 7,258,582 (257)

Development and Analysis of an Exoskeleton for Upper Limb Elbow Joint Rehabilitation Using EEG Signals

Applied System Innovation
Motor impairments significantly affect individuals’ ability to perform activities of daily living, reducing autonomy and quality of life. In response to this, robot-assisted rehabilitation has emerged as an effective and practical solution, enabling ...
Christian Armando Castro-Moncada, Alan Francisco Pérez-Vidal, Gerardo Ortiz-Torres, Felipe De Jesús Sorcia-Vázquez, Jesse Yoe Rumbo-Morales, José-Antonio Cervantes, Carmen Elvira Hernández-Magaña, María Dolores Figueroa-Jiménez, Jorge Aurelio Brizuela-Mendoza, Julio César Rodríguez-Cerda   +9 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Decision making process for clinical it investments in a public health care organization – contingency approach to support the investment decision process

Finnish Journal of eHealth and eWelfare, 2015
Purpose Health care organizations are lacking a clear decision-making framework in IT investment decisions. This study aims at finding a practical tool able to take the different financial and non-financial factors into account.
Johanna Lamminen, Heikki Forsvik, Ville Voipio, Lasse Lehtonen   +3 more
doaj  

Advances in non-invasive EEG-based brain-computer interfaces: Signal acquisition, processing, emerging approaches, and applications

Brain-computer interfaces (BCIs) have revolutionized the field of human-computer interaction, enabling direct communication between the human brain and external devices.
Kumar, S, Sharma, A
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

A computer based education system for signal processing [PDF]

, 1996
Tässä työssä tutkitaan tietokoneavusteista opetusta (TAO) signaalinkäsittelyssä. Työ koostuu signaalinkäsittelyyn soveltuvan TAO-ympäristön kehittämisestä ja esimerkkisovelluksen "Introduction to Signal Processing" rakentamisesta.
Rahkila, Martti
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Review of Health Monitoring and Intelligent Fault Diagnosis for High-Strength Bolts: Failure Mechanisms, Multi-Modal Sensing, and Data-Driven Approaches

Buildings
High-strength bolted connections are fundamental load-bearing components in critical engineering infrastructures such as wind turbines, bridges, and heavy machinery.
Yingjie Wang, Guanghui Chu, Zhifang Sun, Fei Yang, Jun Yang, Xiaoli Sun, Yi Zhao, Shuai Teng   +7 more
doaj   +1 more source