Results 91 to 100 of about 7,258,582 (257)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Bispectral analysis of heart rate variability signal

, 2002
11th European Signal Processing Conference, EUSIPCO 2002 --3 September 2002 through 6 September 2002 -- --This article explores the potential of third-order statistics to analysis of heart rate variability (HRV) signal. Bispectral analysis of short-term
Birand, A., Saliu, Sokol, Kudaiberdieva, G., Saliu S., Birand A., Kudaiberdieva G.   +5 more
core   +1 more source

Computed Tomography (CT) Image Quality Enhancement via a Uniform Framework Integrating Noise Estimation and Super-Resolution Networks

Sensors, 2019
Computed tomography (CT) imaging technology has been widely used to assist medical diagnosis in recent years. However, noise during the process of imaging, and data compression during the process of storage and transmission always interrupt the image ...
Jianning Chi, Yifei Zhang, Xiaosheng Yu, Ying Wang, Chengdong Wu   +4 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Enhancing resolution and image quality in musculoskeletal MRI using deep learning reconstruction

European Radiology Experimental
Objective Deep learning-based noise reduction enhances image quality, overcoming the tradeoff among acquisition time, spatial resolution, and signal-to-noise ratio (SNR). We implemented deep learning reconstruction (DLR) into a 1.5-T musculoskeletal (MSK)
Marco Porta, Giuseppe Agresti, Maria Marcella Laganà, Stefano Orofino, Sara Pangaro, Nicola Carapella, Pietro Andrea Bonaffini, Paolo Bernasconi, Eugenio Annibale Genovese, Sandro Sironi, Alberto Aliprandi   +10 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Research on the Extraction of Digital Features of Vocal Performance Styles and the Construction of a Database for Inheritance and Protection

Advanced Electromagnetics
With the paradigm shift in vocal art research, transforming highly abstract and experience-dependent vocal performance styles into quantifiable and analyzable digital objects has become an important issue in music information processing and digital ...
Q. Duan
doaj   +1 more source

Can surgical simulation be used to train detection and classification of neural networks?

Healthcare Technology Letters, 2017
Computer-assisted interventions (CAI) aim to increase the effectiveness, precision and repeatability of procedures to improve surgical outcomes. The presence and motion of surgical tools is a key information input for CAI surgical phase recognition ...
Odysseas Zisimopoulos, Evangello Flouty, Mark Stacey, Sam Muscroft, Petros Giataganas, Jean Nehme, Andre Chow, Danail Stoyanov   +7 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source