Results 81 to 90 of about 7,258,582 (257)

Computer aided system for learning signal processing

, 2007
This paper describes the educational utility named casSP when studying digital signal processing. casSP offers a GUI support for integrating signal processing demos using plugins described in XML format and executing Octave/Matlab functions.
I. Ruiz, B. Garcia, A. Mendez, O. Lage, Vicente, J., Mendez, A., Lage, O., García, B., J. Vicente, Ruiz, I.   +9 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Signal Seperation Using Multi-rate Signal Processing

, 2001
In signal separation and channel equalisation, a short delay spread channel can result in high complexity receiver filters. The computational complexity of estimating these filters can be reduced by using multi-rate technique.
Dam, Hai, Dam, Hai Huyen, Nordholm, Sven, Nordberg, Jörgen   +3 more
core  

Ant-Colony Based Near-ML Space-Time Multiuser Detection for the STBC Assisted DS-CDMA Uplink

, 2010
In this contribution, a novel Ant Colony Optimization (ACO) based Space-Time (ST) Multiuser Detection (MUD) algorithm was proposed in order to improve the Bit Error Ratio (BER) versus Signal-to-Noise Ratio (SNR) performance achieved by the Space-Time ...
Yang, Lie-Liang, Chong Xu, Lie-Liang Yang, Xu, Chong, Hanzo, Lajos, Lajos Hanzo   +5 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Computer-based and screencasts approach in the signal processing basics electrical engineering course: does blended-learning work to motivate students? [PDF]

, 2016
This paper presents the first experience of the computer-based and screencast approach used in the Signal Processing Basics course to motivate first year electrical engineering students to assess own knowledge and skills.
Sommen, PCW Piet, Gomez Puente, S.M., Gomez Puente, SM, Sommen, P.C.W.   +3 more
core   +1 more source