Results 71 to 80 of about 7,822,395 (293)

The clinical applications of brain–computer interfaces

Brain-X
With the establishment of interdisciplinary platforms in medical engineering, the twenty‐first century has witnessed rapid advancements in brain‒computer interface (BCI) technology, demonstrating significant potential in clinical applications.
Chao‐Ran Jia, Jian‐Wei Huang, Ying‐Qing Hu, Hai‐Yun Zhou, Hong‐Yu Liu, Xin Liu, Hai Zhang, Zu‐Cheng Shen, Wen‐Sheng Li, Shuang‐Qi Gao, Ying Guo   +10 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Computerized invasive measurement of time-dependent intraocular pressure

Brazilian Journal of Medical and Biological Research, 2006
Several methods have been described to measure intraocular pressure (IOP) in clinical and research situations. However, the measurement of time varying IOP with high accuracy, mainly in situations that alter corneal properties, has not been reported ...
T.V.O. Campos, S. Jacobovitz, H.G. Almeida, A.R. Massensini, M.F.D. Moraes   +4 more
doaj  

An Open CAPT System for Prosody Practice: Practical Steps towards Multilingual Setup

Languages
This paper discusses the challenges posed in creating a Computer-Assisted Pronunciation Training (CAPT) environment for multiple languages. By selecting one language from each of three different language families, we show that a single environment may be
John Blake, Natalia Bogach, Akemi Kusakari, Iurii Lezhenin, Veronica Khaustova, Son Luu Xuan, Van Nhi Nguyen, Nam Ba Pham, Roman Svechnikov, Andrey Ostapchuk, Dmitrei Efimov, Evgeny Pyshkin   +11 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Teaching Digital Signal Processing with a Challenge on Image Forensics

, 2019
With the advent of ubiquitous sensing and real-time data processing, the demand for engineers with solid signal processing skills has exceeded the supply by a large margin.
Bohme, R., Pasquini, C., Boato, G.
core   +1 more source

Modelling and studying the effect of graph errors in graph signal processing

, 2021
Publisher Copyright: © 2021The first step for any graph signal processing (GSP) procedure is to learn the graph signal representation, i.e., to capture the dependence structure of the data into an adjacency matrix.
Miettinen, Jari, Ollila, Esa, Vorobyov, Sergiy A., Jari Miettinen, Esa Ollila, Sergiy A. Vorobyov   +5 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source