Results 51 to 60 of about 97,739 (268)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Phosphorelays provide tunable signal processing capabilities for the cell [PDF]

open access: yes, 2013
Achieving a complete understanding of cellular signal transduction requires deciphering the relation between structural and biochemical features of a signaling system and the shape of the signal-response relationship it embeds.
Luca Cardelli   +23 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Computer-based and screencasts approach in the signal processing basics electrical engineering course: does blended-learning work to motivate students? [PDF]

open access: yes, 2016
This paper presents the first experience of the computer-based and screencast approach used in the Signal Processing Basics course to motivate first year electrical engineering students to assess own knowledge and skills.
Sommen, PCW Piet   +3 more
core  

Teaching Digital Signal Processing with a Challenge on Image Forensics

open access: yes, 2019
With the advent of ubiquitous sensing and real-time data processing, the demand for engineers with solid signal processing skills has exceeded the supply by a large margin.
Bohme, R., Pasquini, C., Boato, G.
core   +1 more source

Current Trends in Joint Audio-Video Signal Processing: a Review [PDF]

open access: yes, 2005
Multimodal signal processing has gained a lot of significance in recent years due to advances in computer technology as well as more sophisticated sensors being available.One example is the joint processing of audio and video signals in a variety of ...
Goecke, Roland; id_orcid, Goecke, Roland
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The clinical applications of brain–computer interfaces

open access: yesBrain-X
With the establishment of interdisciplinary platforms in medical engineering, the twenty‐first century has witnessed rapid advancements in brain‒computer interface (BCI) technology, demonstrating significant potential in clinical applications.
Chao‐Ran Jia   +10 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Computerized invasive measurement of time-dependent intraocular pressure

open access: yesBrazilian Journal of Medical and Biological Research, 2006
Several methods have been described to measure intraocular pressure (IOP) in clinical and research situations. However, the measurement of time varying IOP with high accuracy, mainly in situations that alter corneal properties, has not been reported ...
T.V.O. Campos   +4 more
doaj  

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