Results 111 to 120 of about 98,464 (271)
Applied System InnovationMotor impairments significantly affect individuals’ ability to perform activities of daily living, reducing autonomy and quality of life. In response to this, robot-assisted rehabilitation has emerged as an effective and practical solution, enabling ...
Christian Armando Castro-Moncada +9 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Feature detection from echocardiography images using local phase information [PDF]
, 2008 Ultrasound images are characterized by their special speckle appearance, low contrast, and low signal-to-noise ratio. It is always challenging to extract important clinical information from these images.
Rajpoot, Nasir M. (Nasir Mahmood) +3 more
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
A Study of Non-stationary Signal Processing for Machinery Condition Monitoring [PDF]
Machinery condition monitoring techniques are carried out based on the knowledge of the characteristics of signals obtained from a machine or plant. These signals are often non stationary signals whose frequency changes over time due to the time-varying ...
Zhen, Dong
core
Finnish Journal of eHealth and eWelfare, 2015 Purpose Health care organizations are lacking a clear decision-making framework in IT investment decisions. This study aims at finding a practical tool able to take the different financial and non-financial factors into account.
Johanna Lamminen +3 more
doaj
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
BuildingsHigh-strength bolted connections are fundamental load-bearing components in critical engineering infrastructures such as wind turbines, bridges, and heavy machinery.
Yingjie Wang +7 more
doaj +1 more source