Results 61 to 70 of about 256,514 (313)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Compressed sensing of monostatic and multistatic SAR [PDF]

open access: yes, 2013
In this letter, we study the impact of compressed data collections from a synthetic aperture radar (SAR) sensor on the reconstruction quality of a scene of interest.
Çetin, Müjdat   +5 more
core   +1 more source

Comparison of phonendoscopic signal reconstruction techniques for pattern analysis cardiac acoustics

open access: yesRevista Colombiana de Tecnologías de Avanzada
This study evaluates the effectiveness of different techniques of statistical reconstruction of phonocardiographic signals in comparison with classical processing techniques.
Gabriel Felipe Rojas Arango   +1 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

A matrix pencil approach to the existence of compactly supported reconstruction functions in average sampling

open access: yes, 2011
The aim of this work is to solve a question raised for average sampling in shift-invariant spaces by using the well-known matrix pencil theory. In many common situations in sampling theory, the available data are samples of some convolution operator ...
Hernández-Medina, M.A.   +10 more
core   +1 more source

Image compression sensing based on non-local feature fusion network

open access: yesJournal of Radiation Research and Applied Sciences
The emphasis of study in the area of signal processing is image compression. The traditional signal sampling has the problem of signal distortion, and the compressed sensing theory has a good application effect.
Yongping Zhang
doaj   +1 more source

Determination of the Maximum Velocity of Filaments in the in vitro Motility Assay

open access: yesFrontiers in Physiology, 2019
The in vitro motility assay (IVMA) is a powerful tool commonly used in basic muscle research and for drug screenings with the aim to find treatment options for neuromuscular disorders.
Nasrin Bopp   +4 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Signal Reconstruction of Compressed Sensing Based on Alternating Direction Method of Multipliers [PDF]

open access: yes, 2020
The sparse signal reconstruction of compressive sensing can be accomplished by \(l_1\)-norm minimization, but in many existing algorithms, there are the problems of low success probability and high computational complexity. To overcome these problems, an
Zhao, Guoying   +4 more
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

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