Results 111 to 120 of about 1,096,363 (351)

Adrenergic regulation of gluconeogenesis: possible involvement of two mechanisms of signal transduction in alpha 1-adrenergic action. [PDF]

, 1985
J. Adolfo García‐Sáinz, S.M. Teresa Hernández‐Sotomayor   +1 more
openalex   +1 more source

Kinase Mobility Shift Assay (KiMSA) for Assessing Protein Kinase A Activity

Bio-Protocol
The cAMP-dependent protein kinase (PKA) is one of the most extensively distributed kinases among intracellular signal cascades, with a pivotal role in the regulation of various processes, including the capacitation of sperm cells. Traditional assessments
Analia Novero, Tomás Steeman, Catalina Curcio, Lara Buccolini, Andres Binolfi, Diego Krapf, Mariano Buffone, Dario Krapf, Cintia Stival   +8 more
doaj   +1 more source

Distinct functions of AKT isoforms in breast cancer: a comprehensive review

Cell Communication and Signaling, 2019
Background AKT, also known as protein kinase B, is a key element of the PI3K/AKT signaling pathway. Moreover, AKT regulates the hallmarks of cancer, e.g. tumor growth, survival and invasiveness of tumor cells. After AKT was discovered in the early 1990s,
Nico Hinz, Manfred Jücker
doaj   +1 more source

Signal transduction pathways in the clinical approach: where are we going? [PDF]

, 2016
invited ...
LO VASCO, VINCENZA RITA
core   +1 more source

Microtubules and signal transduction

Current Opinion in Cell Biology, 1999
Although molecular components of signal transduction pathways are rapidly being identified, how elements of these pathways are positioned spatially and how signals traverse the intracellular environment from the cell surface to the nucleus or to other cytoplasmic targets are not well understood.
Gregg G. Gundersen, Tiffani A. Cook
openaire   +3 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Synthetic peptide corresponding to a conserved domain of the retroviral protein p15E blocks IL-1-mediated signal transduction. [PDF]

, 1989
Roberta A. Gottlieb, William J. Lennarz, Rebecca D. Knowles, Giuseppe Cianciolo, Charles A. Dinarello, Lawrence B. Lachman, Eugenie S. Kleinerman   +6 more
openalex   +1 more source

Effect of graphene substrate on the SERS Spectra of Aromatic bifunctional molecules on metal nanoparticles [PDF]

, 2016
The design of molecular sensors plays a very important role within nanotechnology and especially in the development of different devices for biomedical applications.
Arenas, J.F., Castro, JL, Lopez-Ramirez, M.R., Otero, J.C., Soto-Martin, Juan   +4 more
core  

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Signal transduction of gamma/delta T cell antigen receptor with a novel mitogenic anti-delta antibody. [PDF]

, 1988
Yujing Wu, W T Tian, R. Michael Snider, Charles W. Rittershaus, P Rogers, L LaManna, S H Ip   +6 more
openalex   +1 more source