Results 141 to 150 of about 4,996,865 (347)
T160‐phosphorylated CDK2 defines threshold for HGF‐dependent proliferation in primary hepatocytes
Molecular Systems Biology, 2015 Liver regeneration is a tightly controlled process mainly achieved by proliferation of usually quiescent hepatocytes. The specific molecular mechanisms ensuring cell division only in response to proliferative signals such as hepatocyte growth factor (HGF)
Stephanie Mueller +10 more
doaj +1 more source
B lymphocyte activation. Transmembrane signal transduction by membrane immunoglobulin in isolated cell membranes. [PDF]
, 1987 L K Harris, John C. Cambier
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Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Postreceptor signal transduction by cyclic adenosine monophosphate and the Ca2+-calmodulin complex. [PDF]
, 1984 Anthony R. Means +2 more
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FEBS Open Bio, EarlyView.FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley +1 more source
FEBS Open Bio, EarlyView.We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang +7 more
wiley +1 more source
Understanding the multifaceted nature of peptide hydrogels in biomedical research
Academia Materials ScienceHydrogels are networks of three-dimensional cross-linked polymers, which possess the capacity to absorb and retain water. Hydrogels have proven to be adaptable and versatile, making them useful in various biomedical applications such as tissue
Srestha Ghosh +3 more
doaj +1 more source
G protein linked signal transduction pathways in development: Dictyostelium as an experimental system [PDF]
, 1989 Richard Firtel +3 more
openalex +1 more source
FEBS Open Bio, EarlyView.By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya +3 more
wiley +1 more source
Synthetic peptide corresponding to a conserved domain of the retroviral protein p15E blocks IL-1-mediated signal transduction. [PDF]
, 1989 Roberta A. Gottlieb +6 more
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