Results 181 to 190 of about 795,179 (316)

Mechanoluminescent HOF Nanotransducers Enabled Sono‐Optogenetics in Parkinsonian Rats

Advanced Functional Materials, EarlyView.
We present a mechanoluminescent system utilizing porous hydrogen‐bonded organic frameworks (HOFs) as a toolkit for focused ultrasound‐triggered, non‐invasive light delivery to the deep brain in rats. This approach enables the specific activation of PV‐GPe neurons in dopamine‐depleted Parkinson's disease rat models, resulting in a comparable alleviation
Wenliang Wang, Ilya Pyatnitskiy, Yanshu Shi, Kai Wing Kevin Tang, Yi Xie, Sihan Yu, Thomas Wynn, Xiangping Liu, Ju‐Chun Hsieh, Jinmo Jeong, Weilong He, Brinkley Artman, Anakaren Romero Lozano, Xi Shi, Arjun Sangani, Lief E Fenno, Samantha Santacruz, Banglin Chen, Huiliang Wang   +18 more
wiley   +1 more source

Phototropin2 LOV1 plays a role in strong light signal transduction leading to chloroplast avoidance response. [PDF]

Acta Physiol Plant
Krzeszowiec W, Nehlin L, Winter N, Bachmair A, Pintscher S, Gabryś H.   +5 more
europepmc   +1 more source

A Skin‐Like Strain Sensor for Real‐Time Human Motion Detection

Advanced Functional Materials, EarlyView.
A skin‐like strain sensor with exceptional flexibility and breathability enables real‐time human motion detection. It offers continuous ECG monitoring and gesture recognition, ensuring high durability and comfort. This innovative design is ideal for wearable applications, combining reliable performance with seamless integration into dynamic ...
Shiqi Song, Zhe Li, Jingya Guo, Shuo Shi, Jian Fang, Xungai Wang   +5 more
wiley   +1 more source

Gαi1/3 Is a Novel Regulatory Target for RANKL Signal Transduction and Osteoporosis. [PDF]

Adv Sci (Weinh)
Bai C, Zhang M, Liu L, Tao L, Xu C, Chai H, Shi X, Wang Y, Zhang X, Chen Q, Liu D, Bai J, She C, Zhou X, Cao C, Shan H.   +15 more
europepmc   +1 more source

Electro‐Steric Ion Confinement in Polyelectrolyte Networks for Robust Nonvolatile Artificial Synapse

Advanced Functional Materials, EarlyView.
Polyelectrolyte stoichiometry governs ion transport and retention in electrolyte‐gated synaptic transistors. A PSS‐rich network creates electro‐steric ion confinement that suppresses ion back‐diffusion and stabilizes channel doping, enabling robust nonvolatile synaptic memory, linear weight updates, and low‐energy operation.
Donghwa Lee, Jinbo Kim, Myeongjin An, Jisoo Park, Junho Sung, Eunsung Hwang, Suhwan Seok, Seong‐Min Bak, Jeonghun Kim, Eunho Lee   +9 more
wiley   +1 more source

An artificial cell capable of signal transduction mediated by ADRB2 for the regulation of glycogenolysis. [PDF]

Nat Commun
Liu Y, Zhao W, Zhao Y, Zhang X, Zhao J, Li S, Ren Y, Han X.   +7 more
europepmc   +1 more source

A Molecular Shielding Strategy to Develop Low Protein Binding, Renal Clearable Pan‐Cancer Near‐Infrared Probes

Advanced Functional Materials, EarlyView.
A molecular shielding strategy to convert “protein‐sticky” and “non‐tumor specific” clinical ICG dye, into a “low protein binding” and “tumor‐targeting” dye with prolonged blood circulation and renal clearance is described. These shielded ICGs demonstrate strong tumor accumulation and optimal tissue clearance, resulting in high tumor‐to‐background ...
Li Xiang, Kailin Mooney, Mingchong Dai, Morgan R. Stewart, Samantha Holland, Michael I. Henderson, Samuel Drennan, Ramon F. Barajas Jr., Jared M. Fischer, Adem Yildirim   +9 more
wiley   +1 more source

Exploiting signal transduction pathways for cancer therapy: insights from natural products in preclinical models. [PDF]

Front Pharmacol
Bukke SPN, Vuyyala B, Thalluri C, Chettupalli AK, Gupta N, Abdullah Almoyad MA, Abdalla SA, Yata VK, Eisa Shogar A, Narapureddy BR, Eftekhari Z, Aja PM, Yadesa TM.   +12 more
europepmc   +1 more source

Transparent and Robust LiCl–Organohydrogel Triboelectric Nanogenerator With Deep Learning Assisted Sensing

Advanced Functional Materials, EarlyView.
Develop a LiCl–PEI–PAM hydrogel with 3000% stretchability and excellent optical transparency. Through comparative studies of various salts, confirm that LiCl is the most suitable salt for high TENG output. Achieve excellent freeze‐resistant, dry‐resistant, and rapid self‐healing (10 s) properties even in extreme environments. Balance ionic conductivity,
Hai Anh Thi Le, Thien Trung Luu, Duc‐Manh Dinh, Kyehan Rhee, Kyungwho Choi, Dukhyun Choi, Yong Tae Park   +6 more
wiley   +1 more source

Gαi1 and Gαi3 mediate IL-11-induced signal transduction and are potential therapeutic targets for LUAD. [PDF]

Cell Death Dis
Luo G, Hu W, Yang J, Lu Z, Cui Y, Zeng W, Ding H, Li Q, Chen Z, Tong X, Ding C, Xu C, Zhao J.   +12 more
europepmc   +1 more source