Results 211 to 220 of about 1,112,644 (355)

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

A <i>Campylobacter jejuni</i> sensor phosphatase-driven two-component system integrates metabolic phosphodonors as cues in signal transduction. [PDF]

Proc Natl Acad Sci U S A
Ruiz N, Hendrixson DR.
europepmc   +1 more source

Quantitative Analysis of Changes in the Molecular Species of Glycerolipids in Cultured Cells during Signal Transduction [PDF]

, 1993
Chung-Hee Lee, Amiya K. Hajra
openalex   +1 more source

Flow‐Induced Vascular Remodeling on‐Chip: Implications for Anti‐VEGF Therapy

Advanced Functional Materials, EarlyView.
Flow‐induced vascular remodeling plays a critical role in network stabilization and function. Using a vasculature‐on‐chip system, this study reveals how physiological VEGF levels and flow affect vascular remodeling and provides insights into tumor vessel normalization.
Fatemeh Mirzapour‐Shafiyi, Elias Huber, Leonie Karr, Johnny Tong, Andreas Richard Bausch, Friedrich Christian Simmel, Karen Alim   +6 more
wiley   +1 more source

Molecular insights into T cell development, activation and signal transduction (Review). [PDF]

Biomed Rep
Omar I, Alakhras A, Mutwali S, Bakhiet M.   +3 more
europepmc   +1 more source

Signal transduction crosstalk in the endocrine system: pancreatic β-cells and the glucose competence concept [PDF]

, 1992
George G. Holz, Joel F. Habener
openalex   +1 more source

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

[Retracted] Correlative study on the JAK‑STAT/PSMβ3 signal transduction pathway in asthenozoospermia. [PDF]

Exp Ther Med
Li J, Zhang L, Li B.
europepmc   +1 more source

Redox regulation of signal transduction: tyrosine phosphorylation and calcium influx.

, 1994
Frank J. T. Staal, Michael T. Anderson, G.E.J. Staal, L A Herzenberg, Carlos Gitler, L A Herzenberg   +5 more
openalex   +1 more source

Transient Stiffness Patterning in Hydrogels Driven by Dissipative Mechanochemical Coupling

Advanced Functional Materials, EarlyView.
Force‐induced disulfide bond rupture in a polymer‐based hydrogel, coupled with chemical or electrochemical reoxidation, leads to the transient modulation of the hydrogel's stiffness properties. High spatiotemporal control is achieved by this dissipative process, enabling the development of out‐of‐equilibrium stiffness patterns and transient, dose ...
Roberto Baretta, Maria F. Pantano, Marco Frasconi   +2 more
wiley   +1 more source