Integrating Inflammatory, Hemodynamic, and Metabolic Cues: Context-Dependent and Mechanosensitive Regulation of Endothelial Notch Signaling in Cardiovascular Disease. [PDF]
Campbell GA, Velazquez OC, Liu ZJ.
europepmc +1 more source
Algorithms for analyzing signals in DNA: Applications to transcription and translation
Markus Friberg
openalex +1 more source
International Symposium on Signal Transduction in Health and Disease on Neuroendocrinology: Basic and Clinical Aspects October 22-24, 2008, Tel Aviv, Israel [PDF]
openalex +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
RXR Gamma Enables Oligodendrocyte Differentiation by Suppressing Sonic Hedgehog Signaling. [PDF]
Baldassarro VA +4 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
The regulatory significance of chondrocyte hypertrophy in maintaining chondrocyte homeostasis, regeneration and repair. [PDF]
Li J +8 more
europepmc +1 more source
A Bi-Objective Traffic Signal Optimization Model for Mixed Traffic Concerning Pedestrian Delays
Görkem Akyol +3 more
openalex +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The Role of Eph/Ephrin-Driven Actomyosin Contractility in Promoting Cell Segregation and Boundary Formation. [PDF]
Shi J, Lyu C.
europepmc +1 more source

