Results 241 to 250 of about 9,547,943 (379)

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

The Evolving Effects of Preference Signaling in the Orthopaedic Residency Match: Outcomes After the Second Year of Preference Signaling Implementation. [PDF]

JB JS Open Access
Dagher T, Guthrie ST, Essey-Stapleton J, Balach T.   +3 more
europepmc   +1 more source

Corrections to the Lick Observatory time-signals for Dec.30.0, Dec. 31.0, Jan. 1.0, and Jan. 2.0

, 1889
J. M. Schæberle
openalex   +1 more source

A Home-Made Wireless Signaling Transmitter [PDF]

, 1905
A. Frederick Collins
openalex   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

To the Editor: Potential Effects of Preference Signaling on International Medical Graduates. [PDF]

J Grad Med Educ
Al-Lami RA.
europepmc   +1 more source

The New Coast Signal Service [PDF]

, 1901
George Ethelbert Walsh
openalex   +1 more source

SMART, a simple modular architecture research tool: identification of signaling domains.

Proceedings of the National Academy of Sciences of the United States of America, 1998
J. Schultz, F. Milpetz, P. Bork, C. Ponting   +3 more
semanticscholar   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

EGFR activation in cholangiocytes promotes extrahepatic bile duct regeneration after injury. [PDF]

Hepatol Commun
Calder AN, Sakaguchi T, Peter M, Tobias J, Frankel T, Razumilava N.   +5 more
europepmc   +1 more source