Results 231 to 240 of about 5,103,566 (350)

Author response for "Inhibition of RNF6 alleviates traumatic brain injury by suppressing STAT3 signaling in rats"

, 2020
Bin Liu, Gang Zhang, Shukun Cui, Guoliang Du   +3 more
openalex   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Integrated Genetic Networks and Epigenetic Regulation inTooth Development and Maturation. [PDF]

Cells
Lee DJ, Won HJ, Shin JO.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Antibody-Drug Conjugates Targeting Resistance-Associated Signaling Pathways: Recent Advances and Future Perspectives. [PDF]

Int J Mol Sci
Xie D, Yang C, Gao S, Li J, Yang J, Li X, Jiang R, Cao F, Zhang S, Wang L, Sun M.   +10 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

PD-1/LAG-3 signaling rewires T-cells via MYC inhibition. [PDF]

Signal Transduct Target Ther
Chocarro L, Fernández-Rubio L, Ausin K, Blanco E, Echaide M, Vilaplana B, Santamaría E, Fernández-Irigoyen J, Kochan G, Escors D.   +9 more
europepmc   +1 more source

Deep Pulse-Signal Magnification for Remote Heart Rate Estimation in Compressed Videos

Joaquim Comas Martínez, Adrià Ruiz, Federico M. Sukno   +2 more
openalex   +1 more source

Faculty Opinions recommendation of Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling.

, 2009
Nadia Rosenthal, Enrique Lara‐Pezzi
openalex   +2 more sources

black signal [PDF]

, 2000
openaire   +1 more source