Results 251 to 260 of about 3,216,633 (318)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Oxidative signaling thresholds shape vulnerability in the central and peripheral nervous systems. [PDF]

PLoS Biol
Wakatsuki S, Araki T.
europepmc   +1 more source

Heme-Mediated Danger Signaling Suppresses Osteogenesis Through TLR4-Dependent Inhibition of β-Catenin Signaling. [PDF]

Int J Mol Sci
Xiang X, Suttorp CM, Wang P, Ongkosuwito EM, Bloemen M, Hoff JWVD, Wagener FADTG.   +6 more
europepmc   +1 more source

Plant resilience: harnessing bioactive compounds for sustainable disease protection. [PDF]

Stress Biol
Latif MZ, Deng M, Asghar N, Kong L, Kousar S, Zhang H, Rehman SU, Jiang Y, Humza M, Lu C, Ding X.   +10 more
europepmc   +1 more source

The ups and downs of human UNC93B1: Autoimmune and viral conditions. [PDF]

J Hum Immun
Idiiatullina E, Casanova JL, Zhang SY.
europepmc   +1 more source

Spleen Tyrosine Kinase in Malignancies and Sepsis: Pathophysiological Roles and Biomarker Potential-A Narrative Review. [PDF]

Biomolecules
Țocu G, Ștefănescu BI, Pleșea Condratovici A, Luțenco V, Stavăr Matei L, Țocu L, Mihailov R, Mihailov OM, Dragostin OM, Tutunaru D, Pelin AM, Hangan LT, Chirilă SI, Cort A, Mehedinți MC, Mocanu E.   +15 more
europepmc   +1 more source