Results 141 to 150 of about 1,476,364 (294)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Mechanisms of Postischemic Stroke Angiogenesis: A Multifaceted Approach

Journal of Inflammation Research
Bin Hu,1 Jingchun Pei,1 Cheng Wan,1,2 Shuangshuang Liu,1 Zhe Xu,3,4 Yongwei Zou,1 Zhigao Li,1 Zhiwei Tang1 1Department of Neurosurgery, The First Affiliated Hospital of Kunming Medical University, Kunming, People’s Republic of China; 2Department of ...
Hu B, Pei J, Wan C, Liu S, Xu Z, Zou Y, Li Z, Tang Z   +7 more
doaj  

Correction: Signaling pathways and targeted therapy for pulmonary hypertension. [PDF]

Signal Transduct Target Ther
Adu-Amankwaah J, Shi Y, Song H, Ma Y, Liu J, Wang H, Yuan J, Sun K, Hu Q, Tan R.   +9 more
europepmc   +1 more source

Reactivation of the PI3K/mTOR Signaling Pathway Confers Resistance to the FGFR4 Inhibitor FGF401 [PDF]

Hung Huynh, Wai Har Ng
openalex   +1 more source

The cGAS-cGAMP-STING Pathway of Cytosolic DNA Sensing and Signaling [PDF]

, 2014
Xin Cai, Yu‐Hsin Chiu, Zhijian J. Chen
openalex   +1 more source

The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways

, 2022
Milton Pereira, Danielle Fernandes Durso, Clare Bryant, Evelyn A. Kurt‐Jones, Neal Silverman, Douglas T. Golenbock, Ricardo T. Gazzinelli   +6 more
openalex   +1 more source

Signaling Pathway [PDF]

, 2020
openaire   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Unraveling the Impact of KRAS Accessory Proteins on Oncogenic Signaling Pathways. [PDF]

Cells
Garg V, Hofmann RNHM, Saleem M, Mirzaiebadizi A, Hashemi GS, Hameed T, Jooyeh B, Pudewell S, Mehrabipour M, Mosaddeghzadeh N, Piekorz RP, Ahmadian MR.   +11 more
europepmc   +1 more source

Imperatorin ameliorates metabolic dysfunction‐associated fatty liver disease through modulating Suv39h1/Fabps/Cept1 signalling pathway [PDF]

Yi Sun, Changyuan Wang, Yang Wang, Ruyi Hao, Lu Liu, Yue Jin, Huijun Sun   +6 more
openalex   +1 more source