Results 211 to 220 of about 31,177,116 (343)

Neuroprotection of retinal ganglion cells in vivo using the activation of the endogenous cannabinoid signaling system in mammalian eyes. [PDF]

Neuronal Signal, 2022
Maguire G, Eubanks C, Ayoub G.
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

The Blueprint of Logical Decisions in a NF-κB Signaling System. [PDF]

ACS Omega
Gautam P, Sinha SK.
europepmc   +1 more source

Control of Cell Size by c-di-GMP Requires a Two-Component Signaling System in the Cyanobacterium <i>Anabaena</i> sp. Strain PCC 7120. [PDF]

Microbiol Spectr, 2023
Sun QX, Huang M, Zhang JY, Zeng X, Zhang CC.   +4 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

The CpxAR signaling system confers a fitness advantage for flea gut colonization by the plague bacillus. [PDF]

J Bacteriol
Robin B, Dewitte A, Alaimo V, Lecoeur C, Pierre F, Billon G, Sebbane F, Bontemps-Gallo S.   +7 more
europepmc   +1 more source

The Role of the Two-Component QseBC Signaling System in Biofilm Formation and Virulence of Hypervirulent Klebsiella pneumoniae ATCC43816. [PDF]

Front Microbiol, 2022
Lv J, Zhu J, Wang T, Xie X, Wang T, Zhu Z, Chen L, Zhong F, Du H.   +8 more
europepmc   +1 more source

Heart- and muscle-derived signaling system dependent on MED13 and Wingless controls obesity in Drosophila

Proceedings of the National Academy of Sciences of the United States of America, 2014
Ji‐Hoon Lee, R. Bassel-Duby, E. Olson
semanticscholar   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Application of IoTDB in Intelligent Operation and Maintenance of URT Signaling Systems

Kongzhi Yu Xinxi Jishu
Continually expanding signaling system equipment in urban rail transit (URT) imposes significantly increased demands for collecting, processing, and storing operation and maintenance (O&M) data, including processing data from approximately 300 000 ...
DENG Yongqi, YANG Jiang, YANG Yibin
doaj