Results 201 to 210 of about 19,728,514 (315)

High-Level Expression of Cell-Surface Signaling System Hxu Enhances Pseudomonas aeruginosa Bloodstream Infection. [PDF]

Infect Immun, 2022
Yang F, Zhou Y, Chen P, Cai Z, Yue Z, Jin Y, Cheng Z, Wu W, Yang L, Ha UH, Bai F.   +10 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

The Fem cell-surface signaling system is regulated by ExsA in Pseudomonas aeruginosa and affects pathogenicity. [PDF]

iScience
Li Y, Bhagirath A, Badr S, Zhang P, Chen L, Dadashi M, Surette MG, Duan K.   +7 more
europepmc   +1 more source

Molecular model of a sensor of two-component signaling system. [PDF]

Sci Rep, 2021
Ryzhykau YL, Orekhov PS, Rulev MI, Rulev MI, Vlasov AV, Melnikov IA, Volkov DA, Nikolaev MY, Zabelskii DV, Murugova TN, Chupin VV, Rogachev AV, Gruzinov AY, Svergun DI, Brennich ME, Gushchin IY, Soler-Lopez M, Bothe A, Büldt G, Leonard G, Engelhard M, Kuklin AI, Gordeliy VI.   +22 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

The Blueprint of Logical Decisions in a NF-κB Signaling System. [PDF]

ACS Omega
Gautam P, Sinha SK.
europepmc   +1 more source

Neuroprotection of retinal ganglion cells in vivo using the activation of the endogenous cannabinoid signaling system in mammalian eyes. [PDF]

Neuronal Signal, 2022
Maguire G, Eubanks C, Ayoub G.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The NmpRSTU multi-component signaling system of <i>Myxococcus xanthus</i> regulates expression of an oxygen utilization regulon. [PDF]

J Bacteriol
McAllister CT, Ronk AM, Stenzel MJ, Kirby JR, Bretl DJ.   +4 more
europepmc   +1 more source

The Role of the Two-Component QseBC Signaling System in Biofilm Formation and Virulence of Hypervirulent Klebsiella pneumoniae ATCC43816. [PDF]

Front Microbiol, 2022
Lv J, Zhu J, Wang T, Xie X, Wang T, Zhu Z, Chen L, Zhong F, Du H.   +8 more
europepmc   +1 more source