Results 61 to 70 of about 298,592 (251)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Research on cyclists microscopic behaviour models at signalized intersection

, 2013
In this paper, video cameras and data analysis technologies have been used to collect and analyze image data of bicyclists at two signalized intersections in Beijing.
Haifeng, Jiang, Pengpeng, Jiang, Hun, Han, Tao, Wen   +3 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

OPERATIONAL ANALYSIS OF ISOLATED SIGNALIZED INTERSECTIONS USING THREE TRAFFIC SOFTWARES

Al-Qadisiyah Journal for Engineering Science, 2017
The operation analysis of isolated signalized intersection provides valuable and important information about the performance of transportation system in the city.
Shamil Ahmed Flamarz Al-Arkawazi
doaj  

Analysis of congestion cost at signalized intersection using Vissim 9 (Case study at Demak Ijo Intersection, Sleman)

MATEC Web of Conferences, 2018
Due to imbalance of road capacity and traffic volume, so traffic congestion will be occurred either along the road and intersection. Demak Ijo intersection is one of signalized junction located in the western part of Yogyakarta with high traffic volume ...
Mahmudah Noor, Akbar Rizkie, Muchlisin
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Theoretical Study of Safe Braking Line at Signalized Intersection [PDF]

, 2017
Signalized intersection is an area where most of the drivers have a difficulty in deciding either to run through the intersection or decelerate their vehicles and stop before the stop line.
Abdul Ghafar, Nor Haslinayati
core  

Estimation of Queue Length at Signalized Intersection Under Non-Lane Based Traffic Conditions [PDF]

, 2022
Excessive queue length is formed at approaches of signalized intersection if demand flow rate exceeds the saturation flow. The analysis of approaching flow at signalized intersections make easier to predict the queue length for avoiding traffic ...
Jithender, Jatoth, Mehar, Arpan
core   +1 more source

Modeling Riding and Stopping Behaviors at Motorcycle Box Intersections: A Case Study in Chiang Mai City, Thailand

Infrastructures
A motorcycle box intersection is a signalized intersection with advanced stop lines or stopping spaces intended for motorcycles, creating a waiting area in front of other vehicles.
Wachira Wichitphongsa, Nopadon Kronprasert, Moe Sandi Zaw, Pongthep Pisetsit, Thaned Satiennam   +4 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source