Results 111 to 120 of about 968,312 (333)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

A Dynamics-Informed Non-Causal Deep Learning Framework for High-Precision SOP Positioning Using Low-Quality Data

open access: yesAerospace
Low Earth Orbit (LEO) satellite signals of opportunity (SOP) provide a viable positioning alternative in GNSS (Global Navigation Satellite System)-denied environments, yet their accuracy is fundamentally constrained by the low-quality orbital data ...
Zhisen Wang, Hu Lu, Zhiang Bian
doaj   +1 more source

Performance Limits for Signals of Opportunity-Based Navigation

open access: yesION GNSS+, The International Technical Meeting of the Satellite Division of The Institute of Navigation
Submitted to ION GNSS+
Zanirato, Francesco   +6 more
openaire   +3 more sources

Job Characteristics and Labor Market Discrimination in Promotions: New Theory and Empirical Evidence [PDF]

open access: yes, 2007
[Excerpt] We present new theory and the first empirical test of promotion discrimination models based on job assignment signaling. In our theory, promotions serve as signals of worker ability, and job hierarchies differ in the degree to which tasks vary ...
DeVaro, Jed, Ghosh, Suman, Zoghi, Cindy
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Feasibility Study on Passive-radar Detection of Space Targets Using Spaceborne Illuminators of Opportunity

open access: yesLeida xuebao, 2015
Space target surveillance generally uses active radars. To take full advantage of passive radars, the idea of using spaceborne illuminators of opportunity for space target detection is presented in this paper.
Jiang Tie-zhen   +3 more
doaj   +1 more source

Signals of Opportunity in Low Earth Orbit

open access: yes, 2018
The goal of this dissertation is to perform a preliminary study concerning availability requirements for successful navigation in orbit. A number of signal types will then be studied in order to verify requirement satisfaction, also to assess the feasibility of using signals of opportunity such as DTTV and LTE existent at Low Earth Orbit altitudes. One
openaire   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

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