Results 71 to 80 of about 968,312 (333)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Bistatic scattering simulations of circular and linear polarizations over land surface for signals of opportunity reflectometry

open access: yesGeoscience Letters, 2021
Signals of Opportunity Reflectometry (SoOp-R) employs the communication system, GNSS (Global Navigation Satellite System) constellation and other potential Signals of Opportunity (SoOp) as the transmitters.
Xuerui Wu   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Referenceless Doppler Shift and Rate Estimation for Opportunistic Positioning With OneWeb Signals

open access: yesIEEE Access
We propose a technique for extracting the Doppler shift and its rate from OneWeb’s Ku-band user downlink signals and demonstrate its suitability for opportunistic positioning.
Nabil Jardak, Ronan Adam, Quentin Jault
doaj   +1 more source

Signals of Opportunity for Positioning Purposes

open access: yes, 2018
O ver the last years, location-based services (LBS) have become popular due to the emergence of smartphones with capabilities of positioning their user’s location on Earth at unprecedented speed and convenience. Behind such feat are the technological advances in global navigation satellite systems (GNSS), such as Galileo, Globalnaya Navigazionnaya ...
openaire   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Differential Signals-of-Opportunity Timing Back-Up Method on VHF Band for Critical Infrastructures

open access: yesIEEE Access
This paper describes a back-up method for GNSS-free timing for power lines which is currently achieved using fibre links. The method is based on software-defined-radio technologies for monitoring low-frequency signals of opportunity (SoOp) serving as an ...
Martta-Kaisa Olkkonen   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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