Results 101 to 110 of about 2,398,637 (321)

An intriguing vision for transatlantic collaborative health data use and artificial intelligence development

npj Digital Medicine
Our traditional approach to diagnosis, prognosis, and treatment, can no longer process and transform the enormous volume of information into therapeutic success, innovative discovery, and health economic performance.
Daniel C. Baumgart
doaj   +1 more source

Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer

Frontiers in Immunology
BackgroundFibroblasts can regulate tumour development by secreting various factors. For COAD survival prediction and CAFs-based treatment recommendations, it is critical to comprehend the heterogeneity of CAFs and find biomarkers.MethodsWe identified ...
Wenbing Zhang, Chi Yang, Ye Lu, Ye Lu, Chenling Tang, Mengyu Zhao, Zhaohui Wang, Jidong Gao, Jidong Gao, Shuangjiu Hu, Zhihua Chen   +10 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

New and revised gene ontology biological process terms describe multiorganism interactions critical for understanding microbial pathogenesis and sequences of concern

Journal of Biomedical Semantics
Background There is a new framework from the United States government for screening synthetic nucleic acids. Beginning in October of 2026, it calls for the screening of sequences 50 nucleotides or greater in length that are known to contribute to ...
Gene Godbold, Jody Proescher, Pascale Gaudet   +2 more
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

The Reliability of Smartphone and Goniometric Measurements of Hip Range of Motion

Journal of Rehabilitation Sciences and Research, 2016
Background: Range of motion is an essential component of the hip examination. Handling issues with the goniometer often create challenges when measuring hip passive range of motion (PROM).
Elizabeth S Norris, Emily Wright, Shannon Sims, Megan Fuller, Kurt Neelly   +4 more
doaj  

Unique genetic signatures in HIV-1 subtype A1 and A1D recombinant envelope glycoprotein distinguish contemporary transmitted/founder viruses from historical strains in East Africa

Frontiers in Microbiology
IntroductionThe envelope glycoprotein (Env) of HIV-1 Transmitted/Founder (T/F) viruses in subtypes B and C carries distinct genetic signatures that enhance transmission fitness, augment infectivity and immune evasion.
Frank Kato, Frank Kato, Anne Kapaata, Ronald Galiwango, Ronald Galiwango, Angella Nakyanzi, Christian Ndekezi, Christian Ndekezi, Fortunate Natwijuka, Fortunate Natwijuka, Denis Omara, Denis Omara, Andrew Ekii Obuku, Brian Foley, Pontiano Kaleebu, Pontiano Kaleebu, Eunice Nduati, Sheila Nina Balinda, Sheila Nina Balinda   +18 more
doaj   +1 more source

Estimation of the sky radiance [PDF]

Scientific Technical Review, 2019
For the infrared prefilter model there was a need for testing the sky radiation and defining its fluctuations within the zone of neighborhood area for the current frame and tests of repeatability.
Knežević Dragan, Nikolić Zoran, Mišković Katarina, Vasiljević Darko   +3 more
doaj  

Probing for Leptonic Signatures from GRB030329 with AMANDA-II [PDF]

, 2005
M. Stamatikos, Jenny Kurtzweil, Melanie Clarke   +2 more
openalex   +1 more source

Comprehensive analysis of candidate signatures of long non-coding RNA LINC01116 and related protein-coding genes in patients with hepatocellular carcinoma [PDF]

, 2022
Xiangkun Wang, Kai Luo, Long Yu, Honglei Wang, Xudong Zhang, Renfeng Li   +5 more
openalex   +1 more source