Results 11 to 20 of about 2,398,637 (321)

vcferr: Development, validation, and application of a single nucleotide polymorphism genotyping error simulation framework [version 1; peer review: 1 approved, 2 approved with reservations]

open access: yesF1000Research, 2022
Motivation: Genotyping error can impact downstream single nucleotide polymorphism (SNP)-based analyses. Simulating various modes and levels of error can help investigators better understand potential biases caused by miscalled genotypes. Methods: We have
Bruce Budowle   +7 more
doaj   +1 more source

Mfsd2a-mediated lysolipid transport is important for renal recovery after acute kidney injury

open access: yesJournal of Lipid Research, 2023
Acute kidney injury (AKI) is a global public health concern with high mortality and morbidity. In ischemic–reperfusion injury (IRI), a main cause of AKI, the brush border membrane of S3 proximal tubules (PT) is lost to the tubular lumen.
Randy Y.J. Loke   +14 more
doaj   +1 more source

Black holes, cosmological singularities and change of signature [PDF]

open access: yes, 1994
There exists a widespread belief that signature type change could be used to avoid spacetime singularities. We show that signature change cannot be utilised to this end unless the Einstein equation is abandoned at the suface of signature type change.
Carfora M   +16 more
core   +2 more sources

Pseudorandom signatures [PDF]

open access: yesProceedings of the 8th ACM SIGSAC symposium on Information, computer and communications security, 2013
We develop a three-level hierarchy of privacy notions for (unforgeable) digital signature schemes. We first prove mutual independence of existing notions of anonymity and confidentiality, and then show that these are implied by higher privacy goals.
Fleischhacker, N   +4 more
openaire   +2 more sources

Signature reversal invariance [PDF]

open access: yes, 2006
We consider the signature reversing transformation of the metric tensor g_ab goes to -g_ab induced by the chiral transformation of the curved space gamma matrices gamma_a goes to gamma gamma_a in spacetimes with signature (S,T), which also induces a (-1)^
Duff, M. J., Kalkkinen, Jussi
core   +5 more sources

Prenatal selective serotonin reuptake inhibitor (SSRI) exposure induces working memory and social recognition deficits by disrupting inhibitory synaptic networks in male mice

open access: yesMolecular Brain, 2019
Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed antidepressant drugs in pregnant women. Infants born following prenatal exposure to SSRIs have a higher risk for behavioral abnormalities, however, the underlying mechanisms remains ...
Weonjin Yu   +10 more
doaj   +1 more source

SeqScreen: accurate and sensitive functional screening of pathogenic sequences via ensemble learning

open access: yesGenome Biology, 2022
The COVID-19 pandemic has emphasized the importance of accurate detection of known and emerging pathogens. However, robust characterization of pathogenic sequences remains an open challenge.
Advait Balaji   +13 more
doaj   +1 more source

Flip signatures

open access: yesErgodic Theory and Dynamical Systems, 2022
AbstractA $D_{\infty }$ -topological Markov chain is a topological Markov chain provided with an action of the infinite dihedral group $D_{\infty }$ . It is defined by two zero-one square matrices A and J satisfying $AJ=JA^{\textsf {T}}$ and $J^2=I$ .
openaire   +3 more sources

Classical Signature Change in the Black Hole Topology [PDF]

open access: yes, 1997
Investigations of classical signature change have generally envisaged applications to cosmological models, usually a Friedmann-Lemaitre-Robertson-Walker model.
Ellis, G. F. R.   +2 more
core   +2 more sources

Advances and Remaining Challenges in the Study of Influenza and Anthrax Infection in Lung Cell Culture

open access: yesChallenges, 2018
For over 30 years, immortalized lung cells have enabled researchers to elucidate lung-pathogen molecular interactions. However, over the last five years, numerous commercial companies are now providing affordable, ready-to-use primary lung cells for use ...
Joshua D. Powell, Timothy M. Straub
doaj   +1 more source

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