Results 91 to 100 of about 260,218 (282)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Designated verifier aggregate signature scheme based on SM9
网络与信息安全学报Aggregate signatures have been recognized for significantly improving signing efficiency, reducing the computational cost for signers, lowering communication costs, and better protecting the privacy of signers. Currently, many aggregate signature schemes
Jiguo LI, Chun FANG
doaj +1 more source
Acoustic Sensing Based on Online Handwritten Signature Verification. [PDF]
Sensors (Basel), 2022 Chen M, Lin J, Zou Y, Wu K.
europepmc +1 more source
Offline Signature Verification Scheme [PDF]
, 2009 Offline signature verification schemes are necessary to determine the authenticity and genuineness of a variety of things which require certification using signatures.
Mishra, Prabit Kumar +1 more
core
Selecting reference signatures for on-line signature verification [PDF]
, 1995 Personal stability in signing in one of the key factors for high-accuracy signature verification. In this paper the local stability of a dynamic signature is measured. The acccuracy of an on-line signature verification system is improved by selecting, among a set of specimens available, the subset of reference signatures which is near-optimal for ...
G. CONGEDO +4 more
openaire +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Incorporating signature verification on handheld devices with user-dependent Hidden Markov Models [PDF]
, 2008 Proceedings of the International Conference on Frontiers in Hadwriting Recognition (ICFHR 2008)A dynamic signature verification system based on Hidden Markov Models is presented.
Fiérrez, Julián +2 more
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
AES Based White Box Cryptography in Digital Signature Verification. [PDF]
Sensors (Basel), 2022 Shukla PK +4 more
europepmc +1 more source