Results 71 to 80 of about 260,218 (282)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Template Matching Using Time-Series Averaging and DTW With Dependent Warping for Online Signature Verification

open access: yesIEEE Access, 2019
Online signature verification has been widely applied in biometrics and forensics. Due to the recent demand on high-speed systems in this era of big data, to simultaneously improve its performance and calculation complexity, this study focuses on a ...
Manabu Okawa
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

DWSCNN Online Signature Verification Algorithm Based on CAE-MV Feature Dimensionality Reduction

open access: yesIEEE Access
In recent years, with the rapid advancements in deep learning technologies, particularly deep neural networks, signature verification has seen significant improvements in accuracy. Despite the significant progress made in using deep learning technologies,
Jianbin Zheng   +7 more
doaj   +1 more source

Approaches to online handwritten signature verification

open access: yesБезопасность информационных технологий, 2020
Handwritten signature is one of the most common methods of biometric authentication, where static and dynamic signature characteristics are used to confirm the user's identity.
Anastasia V. Beresneva   +1 more
doaj   +1 more source

Proposal for a two-channel quantum dot setup: Prediction for the capacitance lineshape

open access: yes, 2007
We have made a detailed proposal for a two-channel quantum dot setup. The energy scales in the problem are such that we are able to make connection with the two-channel Anderson model, which, in spite of being well-known in the context of heavy-Fermion ...
Anders   +15 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

iSignDB: A database for smartphone signature biometrics

open access: yesData in Brief, 2020
The signature has long been in use for the user verification. These signatures have user specific features that differentiate the individual for authentication. The signature verification can be offline or online.
Suraiya Jabin   +3 more
doaj   +1 more source

Realising a signature verification using Single Electron Transport Devices. [PDF]

open access: yes, 2012
The need for developing faster systems are a trend today. Binary decision devices, working on the principle of single electrons are much faster and low time consuming.
Singh, Anuja
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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