Results 61 to 70 of about 849,533 (293)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Offline signature verification based on improved extracted features using neural network [PDF]

, 2014
The verification of handwritten signatures is one of the oldest and the most popular biometric authentication methods in our society. A history which spans several hundred years has ensured that it also has a wide legal acceptance all around the world ...
Hussein, Karrar Neamah
core  

DWSCNN Online Signature Verification Algorithm Based on CAE-MV Feature Dimensionality Reduction

IEEE Access
In recent years, with the rapid advancements in deep learning technologies, particularly deep neural networks, signature verification has seen significant improvements in accuracy. Despite the significant progress made in using deep learning technologies,
Jianbin Zheng, Ziyao Chen, Liping Huang, Yifan Gao, Xiangxiang Yu, Hui Wang, Jiamei Yang, Yu Wang   +7 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Accelerating EdDSA Signature Verification with Faster Scalar Size Halving

Transactions on Cryptographic Hardware and Embedded Systems
This paper establishes that the extended Euclidean algorithm (EEA) implemented in a division-free manner is faster than the Lagrange algorithm with a similar level of optimization when it comes to halving the size of scalars found in the equations of ...
Muhammad ElSheikh, İrem Keskinkurt Paksoy, Murat Cenk, M. Anwar Hasan   +3 more
doaj   +1 more source

Template Matching Using Time-Series Averaging and DTW With Dependent Warping for Online Signature Verification

IEEE Access, 2019
Online signature verification has been widely applied in biometrics and forensics. Due to the recent demand on high-speed systems in this era of big data, to simultaneously improve its performance and calculation complexity, this study focuses on a ...
Manabu Okawa
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

iSignDB: A database for smartphone signature biometrics

Data in Brief, 2020
The signature has long been in use for the user verification. These signatures have user specific features that differentiate the individual for authentication. The signature verification can be offline or online.
Suraiya Jabin, Sumaiya Ahmad, Sarthak Mishra, Farhana Javed Zareen   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source