Results 131 to 140 of about 8,975,030 (331)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Scientists rise up against statistical significance

open access: yesNature, 2019
Valentin Amrhein   +2 more
semanticscholar   +1 more source

Significance of machine learning in healthcare: Features, pillars and applications

open access: yesInt. J. Intell. Networks, 2022
M. Javaid   +4 more
semanticscholar   +1 more source

A critical analysis of the role of statistical significance testing in education research: With special attention to mathematics education [PDF]

open access: yes, 2005
This study analyzes the role of statistical significance testing (SST) in education. Although the basic logic underlying SST 一 a hypothesis is rejected because the observed data would be very unlikely if the hypothesis is true 一 appears so obvious that ...
Ng, Yui-kin, Yui-kin Ng,
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The significance of microprogramming

open access: yesACM SIGMICRO Newsletter, 1973
Interest in the topic of microprogramming appears to have had a great growth in the middle and late 1960's, but since that time it has leveled off or declined somewhat. This paper examines the reasons behind this development and then offers a reconsideration of and a new proposal for the definition of microprogramming.This result is supported by the ...
openaire   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

The Punjabi Idioms in Shaikh Rauf and Iqbal Salahud Din's Poetry

open access: yesمجلہ تحقیق
This article looks at how traditional literature through the use of proverbs is a source of influence in poetry. We look at their thinking & proverbs significance and use and try to associate and relate them to aspects of real life.
Syed Farman Ali Shah
doaj   +1 more source

The significance of significant figures

open access: yesClinical Chemistry, 1990
R C, Hawkins, R N, Johnson
openaire   +2 more sources

Home - About - Disclaimer - Privacy