Results 151 to 160 of about 10,843,502 (349)

Talking on historical connotation and significance of nursing aesthetics development

open access: yesHuli yanjiu, 2004
to discuss the historical connotation and significance of nursing aesthetics development from four aspects as: ① nursing aesthetics rooted in nursing essence; ② nursing aesthetics gestating with the founding and developing of nursing science;③ nursing ...
雷鹤, 林爱华, 张银玲, 曹宝花
doaj  

Prognostic significance of uPA and uPAR expression in patients with cervical cancer undergoing radiotherapy

open access: diamond, 2021
Danupon Nantajit   +4 more
openalex   +2 more sources

The Cult of Statistical Significance [PDF]

open access: yes
This article takes issue with a recent book by Ziliak and McCloskey (2008) of the same title. Ziliak and McCloskey argue that statistical significance testing is a barrier rather than a booster for empirical research in many fields and should therefore ...
Walter Kraemer
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Significance of tumor markers in lung cancer [PDF]

open access: bronze, 2006
P. P. Mumbarkar   +2 more
openalex   +1 more source

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