Results 161 to 170 of about 8,975,030 (331)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Targeting the KAT7/H3K14ac/RAC2 Axis Mediates OXPHOS to Promote Stemness Maintenance and Malignancy in Glioblastoma. [PDF]

Adv Sci (Weinh)
Liu J, Sun Y, Zhu Y, Mu G, Wang J, Wang L, Zhao F, Zhao Z, Wang J, He Y, Jiang Z, Li X, Han M, Huang B.   +13 more
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

p-Values and confidence intervals as compatibility measures: guidelines for interpreting statistical studies in clinical research

The Lancet Regional Health - Southeast Asia
Alessandro Rovetta, Luca Piretta, Mohammad Ali Mansournia   +2 more
doaj   +1 more source

Significance of Electromagnetic Potentials in the Quantum Theory

, 1959
Y. Aharonov, D. Bohm
semanticscholar   +1 more source

Pathophysiological Role of Perivascular Macrophages in Blood-Brain Barrier Dysfunction Induced by Cerebral Hypoperfusion in Mice. [PDF]

Neurochem Res
Matsumura S, Moriyama Y, Ochiai A, Iwatani Y, Hayashi H, Takagi N.   +5 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

A Semiotic Cultural Psychology Analysis of Musical Improvisation: Creativity as an Affective-Sociocultural Act. [PDF]

Integr Psychol Behav Sci
Monzo D, Glăveanu VP.
europepmc   +1 more source

Economic Integration of Eurasia: Opportunities and Challenges of Global Significance [PDF]

With the collapse of the Soviet Empire in 1991, a new frontier in the process of globalization of the world economy opened up: the economic integration of the Eurasian "super-continent".
Johannes F. Linn, David Tiomkin
core