On the Role of sIL-2R Measurements in Rheumatoid Arthritis and Cancers [PDF]
Mediators of Inflammation, 2005 A soluble IL-2 receptor (sIL-2R) is a circulating form of a membrane receptor localized on lymphoid and some cancer cells. The biological function of sIL-2R has not been completely understood.
Anna Maria Witkowska
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Clinical significance of sIL-2R levels in B-cell lymphomas. [PDF]
PLoS ONE, 2013 Elevated soluble interleukin-2 receptor (sIL-2R) in sera is observed in patients with malignant lymphoma (ML). Therefore, sIL-2R is commonly used as a diagnostic and prognostic marker for ML, but the mechanisms responsible for the increase in sIL-2R ...
Noriaki Yoshida +16 more
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sIL-2R and sIL-2R/Lymphocyte Ratio as Indicators of Severity in COVID-19 Pediatric Patients [PDF]
Microbes and Infectious Diseases, 2022 Objectives: To determine the role of sIL-2R and sIL-2R/lymphocyte ratio as indicators of COVID-19 severity and predictors of clinical progression among children and adolescents. Patients and Methods: This observational cross-sectional ...
Nourhan Abdelfattah +3 more
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Diagnostic Value of sIL-2R, TNF-α and PCT for Sepsis Infection in Patients With Closed Abdominal Injury Complicated With Severe Multiple Abdominal Injuries [PDF]
Frontiers in Immunology, 2021 ObjectiveWe aimed to evaluate the diagnostic value of soluble interleukin-2 receptor (sIL-2R), tumor necrosis factor-α (TNF-α), procalcitonin (PCT), and combined detection for sepsis infection in patients with closed abdominal injury complicated with ...
Guang-hua Zhai +7 more
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Biological significance of soluble IL-2 receptor [PDF]
Mediators of Inflammation, 1993 A NUMBER of receptors for growth factors and differentiation antigens have been found to be secreted or released by cells. Following mononuclear cell (MNC) activation and interleukin-2 receptor (IL-2R) expression, a soluble form of the Alpha;-chain of IL-
Calogero Caruso +4 more
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Elevation of soluble interleukin-2 receptor levels in nasal allergy [PDF]
Mediators of Inflammation, 1995 To investigate soluble IL-2 receptor (sIL-2R) levels in nasal allergy, the sera and nasal secretions from patients with nasal allergy and from healthy subjects were subjected to a double-epitope enzyme-linked immunosorbent assay. Significant elevation of
K. Hisamatsu +5 more
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Serum Soluble Interleukin-2 Receptor Does Not Differentiate Complex Regional Pain Syndrome from Other Pain Conditions in a Tertiary Referral Setting [PDF]
Mediators of Inflammation, 2020 Previously, we showed that serum soluble interleukin-2 receptor (sIL-2R) levels, a marker for T-cell activation, were higher in complex regional pain syndrome (CRPS) patients than in healthy controls, suggesting pathogenic T-cell activation in CRPS ...
K. D. Bharwani +4 more
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Soluble interleukin-2 receptors in ulcerative colitis [PDF]
Mediators of Inflammation, 1993 T-Cell activation results in the release or shedding of a soluble form (45 kDa) of the cellular (55 kDa) low-affinity interleukin-2 receptor (α-chain) (slL-2R).
O. H. Nielsen, J. Brynskov
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Soluble Interleukin-2 Receptor: A Potential Marker for Monitoring Disease Activity in IgG4-Related Disease [PDF]
Mediators of Inflammation, 2018 Background. IgG4-related disease (IgG4-RD) is a fibroinflammatory condition. T-cells play a crucial role in the pathogenesis, and therefore, serum soluble interleukin-2 receptor (sIL-2R) may be a potential biomarker. Method.
A. F. Karim +5 more
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Soluble interleukin-2 receptor combined with interleukin-8 is a powerful predictor of future adverse cardiovascular events in patients with acute myocardial infarction [PDF]
Frontiers in Cardiovascular Medicine, 2023 BackgroundLittle is known about the role of interleukin (IL) in patients with acute myocardial infarction (MI), especially soluble IL-2 receptor (sIL-2R) and IL-8.
Kunming Pan +16 more
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