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sIL-2R levels predict the spontaneous remission in sarcoidosis

Respiratory Medicine, 2020
Sarcoidosis is associated with a wide range of disease outcomes including spontaneous remission and progressive courses. It is necessary to identify patients with spontaneous remission without corticosteroid treatment. This study aimed to identify the markers for predicting spontaneous remission in patients with sarcoidosis.453 patients diagnosed with ...
Ying, Zhou   +4 more
openaire   +2 more sources

709 Colon cancer: SIL-2R and correlated mechanisms

European Journal of Cancer, 1995
The current research has still not clarified why serum levels of sIL-2R increase in cancer patients. In order to establish whether this could be an independent event or there are correlated mechanisms, in colon cancer patients and controls we examined the level of this soluble receptor in correlation with phenotype of PBMC; serum levels of IL-6, TNF-α,
A.M. Berghella   +7 more
openaire   +1 more source

Clinical implication of serum sIL-2R levels in ovarian cancer

Current Medical Science, 1998
The levels of serum soluble interleukin-2 receptor (sIL-2R) of 36 patients with ovarian cancer, 34 with benign gynecological tumors and 31 blood donors were measured by ELISA. Compared to those of benign and normal controls, serum levels of sIL-2R in patients with ovarian cancer elevated significantly (P < 0.01). Serum sIL-2R levels were likely related
S, Wang, G, Cai, Y, Lu
openaire   +2 more sources

Serum TNF-α, sCD8 and sIL-2R levels in childhood tuberculosis

Infection, 1995
In this study we have determined the serum tumor necrosis factor-alpha (TNF-alpha), soluble CD8 (sCD8) and soluble interleukin-2 receptor (sIL-2R) levels in children with active pulmonary tuberculosis (n = 66) and healthy controls (n = 20). Measurable serum TNF-alpha levels were detected in nine of 86 children (10.5%), all of whom belonged to the group
I B, Barlan   +4 more
openaire   +2 more sources

Soluble interleukin 2 receptor (sIL‐2R) levels in renal transplant recipients

Clinical Transplantation, 2004
Abstract:  Background:  Allograft rejection is associated with T cell activation. T cell activation leads to secretion of soluble IL‐2 receptor and elevated serum soluble IL‐2 receptor (sIL‐2R) levels. However, the clinical implication of individual elevated sIL‐2 receptor levels is unclear. We followed levels of sIL‐2R pre‐ and post‐transplantation to
Rajil, Mehta   +3 more
openaire   +2 more sources

Serum soluble interleukin 2 (IL-2) receptor (sIL-2R) in differentiated thyroid carcinoma

Journal of Endocrinological Investigation, 1994
Increased concentrations of serum soluble interleukin-2 (IL-2) receptor (sIL-2R), a marker of T-lymphocyte activation, have been found in several metastatic solid tumors. To our knowledge, no information is available on serum sIL-2R in differentiated thyroid carcinoma (DTC).
MARIOTTI, STEFANO   +7 more
openaire   +4 more sources

Soluble interleukin-2 receptor (sIL-2R) in coeliac disease

1990
Activation of T lymphocytes with mitogens or specific antigen induces the synthesis of interleukin-2 (IL-2) and the expression of specific cell surface receptors (IL-2R) for this growth factor [l]. The IL-2 receptor consists of at least two IL-2 binding polypeptides with different binding affinities [2].
J E Crabtree   +4 more
openaire   +1 more source

[Soluble interleukin 2 receptor (sIL-2R) in chronic polyarthritis].

Zeitschrift fur Rheumatologie, 1990
An ELISA was used to measure soluble interleukin-2 receptor (sIL-2R) in the sera and synovial fluid (SF) of patients with rheumatoid arthritis (RA). Patients with seropositive, as well as seronegative RA had raised levels of sIL-2R in serum and SF compared to patients with osteoarthritis and sex-age matched healthy subjects.
C, Herzog   +4 more
openaire   +1 more source

T cell subsets and sIL-2R/IL-2 levels in patients with glaucoma

American Journal of Ophthalmology, 2001
We hypothesize that cellular immunity may have a previously unrecognized role in glaucomatous optic neuropathy. The purpose of this study is to analyze subsets of T cells and the levels of cytokine IL-2 and the soluble IL-2 receptor in peripheral blood from patients with normal pressure glaucoma (NPG) or primary open angle glaucoma (POAG) in comparison
J, Yang   +4 more
openaire   +2 more sources

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