Results 21 to 30 of about 55,581 (203)
Analysis of Soluble Interleukin‐2 Receptor as a Prognostic Biomarker in NMOSD and MOGAD [PDF]
Annals of Clinical and Translational NeurologyObjective Soluble interleukin‐2 receptor (sIL‐2R) is a biomarker for T cell activity. T cells are involved in neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) pathogenesis ...
Philipp Klyscz +8 more
doaj +2 more sources
Comparison of serum sIL-2R and LDH levels in patients with intravascular large B-cell lymphoma and patients with advanced stage diffuse large B-cell lymphoma. [PDF]
J Clin Exp Hematop, 2023 Intravascular large B-cell lymphoma (IVL) is a rare type of lymphoma characterized by tumor growth selectively within the vessels. The 5th edition of the World Health Organization classification defines IVL as a large B-cell lymphoma, the same as diffuse
Hirami Y +7 more
europepmc +3 more sources
Impaired activation of STAT5 upon IL-2 stimulation in Tregs and elevated sIL-2R in Sjögren's syndrome. [PDF]
Arthritis Res Ther, 2022 BACKGROUND: Interleukin-2 (IL-2) and the high-affinity IL-2 receptor (IL-2R) are essential for the survival of regulatory T cells (Tregs) which are the main players in immune tolerance and prevention of autoimmune diseases.
Keindl M +7 more
europepmc +2 more sources
sIL-2R- an Immuno-biomarker for Prediction of Metastases in Uveal Melanoma [PDF]
Anticancer Research, 2022 Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. High serum levels of soluble IL-2 receptor (sIL-2R) have been reported in acute inflammations and metastatic cancers. This study evaluated the potential of high/increasing sIL-2R levels in predicting metastases.The study included a total of 1,546 sera samples of subjects ...
Vivian, Barak +2 more
openaire +2 more sources
sIL-2R: A Novel Diagnostic Biomarker for Primary Adrenal Lymphoma
The Journal of Clinical Endocrinology & Metabolism, 2022 Abstract Context Primary adrenal lymphoma (PAL) is difficult to distinguish from other adrenal masses. Soluble interleukin-2 receptor (sIL-2R) is a diagnostic biomarker for nodal non-Hodgkin lymphoma, whose association with PAL is unknown. Objective
Kai Yu +12 more
openaire +2 more sources
All Life, 2023 Introduction: Measuring soluble interleukin-2 receptor (sIL-2R) might be useful for diagnosis and monitoring of immune-mediated diseases. The study investigated factors associated with serum sIL-2R concentrations in adults.
Vanessa Alende-Castro +6 more
doaj +1 more source
BMC Ophthalmology, 2022 Background Intraocular lymphoma (IOL) is a masquerade syndrome that mimics uveitis, making diagnosis difficult. The serum soluble interleukin-2 receptor (sIL-2R), which is cleaved by matrix metalloproteinase (MMP) -2 and MMP-9, has been recognized as a ...
Kayo Suzuki +9 more
doaj +1 more source
Scientific Reports, 2023 Patients with DLBCL achieving complete metabolic response (CMR) after initial treatment with R-CHOP generally have a favourable prognosis; however, there are no established prognostic biomarkers for relapse in these patients.
Yuko Shirouchi +12 more
doaj +1 more source
Renal Failure, 2020 Background Elevated serum levels of sIL-2R are commonly observed in patients undergoing maintenance hemodialysis (MHD). However, the clinical implications in these subjects are unclear.
Xiaohong Chen +8 more
doaj +1 more source
Mediators of Inflammation, 2020 Previously, we showed that serum soluble interleukin-2 receptor (sIL-2R) levels, a marker for T-cell activation, were higher in complex regional pain syndrome (CRPS) patients than in healthy controls, suggesting pathogenic T-cell activation in CRPS ...
K. D. Bharwani +4 more
doaj +1 more source