Results 21 to 30 of about 10,639 (217)

Peroxisome Proliferator-Activated Receptor alpha (PPAR alpha) down-regulation in cystic fibrosis lymphocytes [PDF]

, 2006
Background: PPARs exhibit anti-inflammatory capacities and are potential modulators of the inflammatory response. We hypothesized that their expression and/or function may be altered in cystic fibrosis (CF), a disorder characterized by an excessive host ...
C Hubeau, RB Moss, P Reineck, AA Ionescu, LS Nixon, ME Poynter, P Delerive, SW Chung, BM Forman, W Wahli, JD Tugwood, JM Shipley, A Madej, JP Despres, N Marx, B Staels, Z Israelian-Konaraki, A Trifilieff, MA Birrell, M Roulet, PM Farrell, AP Sampson, JT Zakrzewski, J Carlstedt-Duke, SD Freedman, SM Loitsch, KA Kreuzer, JL Su, JD Dignam, TP Dean, K Balough, TZ Khan, A Augarten, F Akbiyik, I Inoue, DC Jones, P Greally, E Dagli, TA Waldmann, JH Parmentier, K Beier, C Andersson, M Ollero, H Pall, G Chinetti, PR Devchand, N Marx, AE Lovett-Racke, A Linden, F McAllister, RB Moss, RB Moss, C Hubeau, RU Sorensen   +53 more
core   +1 more source

Clinical value of soluble interleukin-2 receptor in infectious complications. [PDF]

, 1994
In this study, we investigated serum-soluble interleukin-2 receptor (sIL-2r) and neopterin (NPT) levels in five patients with severe postoperative infections. A total of 25 synchronous determinations of sIL-2r and NPT were performed. A marked increase in
Hizuta, Akio, Iwadou, Hironori, Iwagaki, Hiromi, Orita, Kunzo, Perdomo, Jose Antonio, Tanaka, Noriaki   +5 more
core   +1 more source

Role of soluble interleukin-2 receptor (sIL-2R) as a predictor for severe dengue infection. [PDF]

Sci Rep
Annually, around half a million people with severe dengue require hospitalization, all over the globe, with around 12,500 (2.5%) succumbing to the illness. In this prospective observational study, we recruited 74 patients with dengue infection, 28 had severe dengue and 46 had dengue with warning signs.
Singh AD, Saroch A, Pannu AK, Yadav AK, Sharda SC, Bhatia M, Kamboj K.   +6 more
europepmc   +4 more sources

Biological significance of soluble IL-2 receptor

Mediators of Inflammation, 1993
A NUMBER of receptors for growth factors and differentiation antigens have been found to be secreted or released by cells. Following mononuclear cell (MNC) activation and interleukin-2 receptor (IL-2R) expression, a soluble form of the Alpha;-chain of IL-
Calogero Caruso, Giuseppina Candore, Diego Cigna, Antonio Tobia Colucci, Maria Assunta Modica   +4 more
doaj   +1 more source

Interleukin-2 Receptor Positive Cells and Circulating Soluble Interleukin-2 Receptors in Patients with Solid Tumors are not Correlated

The International Journal of Biological Markers, 1989
Activated lymphocytes can release a soluble form of IL-2 receptor (sIL-2R), which retains the capacity to bind IL-2. Abnormally high values of sIL-2R have been observed in patients with advanced solid tumors.
P. Lissoni, V. Rizzo, S. Barni, R. Rescaldani, F. Rovelli, A. Biondi, C. Archili, F. Frigerio, G. Tancini   +8 more
doaj   +1 more source

Pleural Fluid Soluble Interleukin-2 Receptor as a Biomarker for the Diagnosis of Tuberculosis Pleural Effusion: A Systematic Review and Meta-Analysis

Journal of Tropical Medicine, 2022
Background. Several studies have assessed the diagnostic accuracy of pleural fluid soluble interleukin-2 receptor (sIL-2R) for tuberculous pleural effusion (TPE) but with varied results. Therefore, we conducted this systematic review and meta-analysis to
Zhi Yan, Hua Wang, Wen-Qi Zheng, Zhi-De Hu   +3 more
doaj   +1 more source

Relationship between serum level of interleukin-2 in patients with systemic lupus erythematosus and disease activity in comparison with control group [PDF]

, 2014
Background: Despite the large number of surveys, there are not any validated biomarkers for SLE disease activity till now. This study aimed to evaluate the relationship between serum level of IL-2 in patients with SLE and disease activity in comparison ...
Sedighi, S., Aghaei, M., Musavi, S., Nomali, M.   +3 more
core   +1 more source

Soluble IL-2 Receptor in Dermatomyositis: Its Associations with Skin Ulcers and Disease Activity

Mediators of Inflammation, 2020
Objective. To investigate the role of soluble interleukin-2R (sIL-2R) in idiopathic inflammatory myopathies (IIM). Methods. Serum sIL-2R levels were measured in 74 dermatomyositis (DM), 16 immune-mediated necrotizing myopathy (IMNM), 24 rheumatoid ...
Linrong He, Xiaoming Shu, Xia Liu, Yongpeng Ge, Sizhao Li, Xin Lu, Guochun Wang   +6 more
doaj   +1 more source

Cytokines and depression in cancer patients and caregivers. [PDF]

, 2017
Objective:A better understanding of the biobehavioral mechanisms underlying depression in cancer is required to translate biomarker findings into clinical interventions.
Boutros, Paul C, Kouzmina, Ekaterina, Li, Madeline, McCusker, Megan, Paige, Christopher J, Rodin, Danielle, Rodin, Gary   +6 more
core   +2 more sources

EVALUATION OF SERUM SOLUBLE INTERLEUKIN -2 RECEPTOR LEVEL IN DIAGNOSIS OF RHEUMATOID ARTHRITIS

The Iraqi Journal of Medical Sciences, 2016
Background: soluble interleukin-2 receptor (sIL-2R) is secreted by lymphocytes upon activation and has been used as a marker of immune activation in several diseases. Objective: This study aimed to assess the potential clinical utility of serum level of
Eham Amir Ali
doaj   +6 more sources