Results 11 to 20 of about 55,581 (203)

Clinical significance of sIL-2R levels in B-cell lymphomas. [PDF]

PLoS ONE, 2013
Elevated soluble interleukin-2 receptor (sIL-2R) in sera is observed in patients with malignant lymphoma (ML). Therefore, sIL-2R is commonly used as a diagnostic and prognostic marker for ML, but the mechanisms responsible for the increase in sIL-2R ...
Noriaki Yoshida, Miyo Oda, Yoshiaki Kuroda, Yuta Katayama, Yoshiko Okikawa, Taro Masunari, Megumu Fujiwara, Takashi Nishisaka, Naomi Sasaki, Yoshito Sadahira, Keichiro Mihara, Hideki Asaoku, Hirotaka Matsui, Masao Seto, Akiro Kimura, Koji Arihiro, Akira Sakai   +16 more
doaj   +6 more sources

On the Role of sIL-2R Measurements in Rheumatoid Arthritis and Cancers [PDF]

Mediators of Inflammation, 2005
A soluble IL-2 receptor (sIL-2R) is a circulating form of a membrane receptor localized on lymphoid and some cancer cells. The biological function of sIL-2R has not been completely understood.
Anna Maria Witkowska
doaj   +5 more sources

ACE and sIL-2R correlate with lung function improvement in sarcoidosis during methotrexate therapy [PDF]

Respiratory Medicine, 2015
In sarcoidosis, the search for disease activity markers that correlate with treatment response is ongoing. The aim of this study was to investigate the pattern of two proposed markers, serum angiotensin-converting enzyme (ACE) and soluble IL-2 receptor (sIL-2R) during methotrexate (MTX) therapy in sarcoidosis patients.We analysed 114 sarcoidosis ...
Adriane D M Vorselaars, Coline H M Van Moorsel, Pieter Zanen   +2 more
exaly   +4 more sources

Role of soluble interleukin-2 receptor (sIL-2R) as a predictor for severe dengue infection. [PDF]

Sci Rep
Annually, around half a million people with severe dengue require hospitalization, all over the globe, with around 12,500 (2.5%) succumbing to the illness. In this prospective observational study, we recruited 74 patients with dengue infection, 28 had severe dengue and 46 had dengue with warning signs.
Singh AD, Saroch A, Pannu AK, Yadav AK, Sharda SC, Bhatia M, Kamboj K.   +6 more
europepmc   +5 more sources

sIL-2R and sIL-2R/Lymphocyte Ratio as Indicators of Severity in COVID-19 Pediatric Patients

Microbes and Infectious Diseases, 2022
Objectives: To determine the role of sIL-2R and sIL-2R/lymphocyte ratio as indicators of COVID-19 severity and predictors of clinical progression among children and adolescents. Patients and Methods: This observational cross-sectional study enrolled 76 pediatric patients [40 (52.6%) males and 36 (47.4%) females] with confirmed COVID-19 ...
Nourhan Abdelfattah, Maha Fathy, Heba Ali, Walaa Khater   +3 more
openaire   +5 more sources

Fulminant hepatitis and elevated levels of sIL-2R in thyroid storm. [PDF]

Endocrinol Diabetes Metab Case Rep, 2019
Summary We report the case of a 48-year-old man with thyroid storm associated with fulminant hepatitis and elevated levels of soluble interleukin-2 receptor (sIL-2R). Fatigue, low-grade fever, shortness of breath, and weight loss developed over several months.
Tanaka Y, Uchida T, Yamaguchi H, Kudo Y, Yonekawa T, Nakazato M.   +5 more
europepmc   +5 more sources

Diagnostic Value of sIL-2R, TNF-α and PCT for Sepsis Infection in Patients With Closed Abdominal Injury Complicated With Severe Multiple Abdominal Injuries [PDF]

Frontiers in Immunology, 2021
ObjectiveWe aimed to evaluate the diagnostic value of soluble interleukin-2 receptor (sIL-2R), tumor necrosis factor-α (TNF-α), procalcitonin (PCT), and combined detection for sepsis infection in patients with closed abdominal injury complicated with ...
Guang-hua Zhai, Wei Zhang, Ze Xiang, Li-Zhen He, Li-Zhen He, Wei-wei Wang, Jian Wu, An-quan Shang   +7 more
doaj   +2 more sources

18F-FDG PET, genotype-corrected ACE and sIL-2R in newly diagnosed sarcoidosis [PDF]

European Journal of Nuclear Medicine and Molecular Imaging, 2009
Angiotensin-converting enzyme (ACE) and soluble interleukin-2 receptor (sIL-2R) are serological markers, widely used for determining sarcoidosis activity. (18)F-FDG PET has proven to be a sensitive technique in the imaging of sarcoidosis. The aim of this study was to determine sensitivity of (18)F-FDG PET, genotype-corrected ACE and sIL-2R in active ...
Keijsers, R.G., Verzijlbergen, F.J., Oyen, W.J.G., Bosch, J.M. van den, Ruven, H.J., Velzen-Blad, H. van, Grutters, J.C.   +6 more
openaire   +4 more sources

Soluble interleukin-2 receptor (sIL-2R) is a marker of disease activity in psoriasis: a comparison of sIL-2R, sCD27, sCD4, sCD8 and sICAM-1.

Acta Dermato-Venereologica, 1996
Psoriasis is a T-cell-mediated inflammatory skin disease which can be treated successfully with immunosuppressive drugs. Our purpose was to evaluate disease activity of psoriasis and the effect of immunosuppressive treatment by monitoring the soluble T-cell products sIL-2R, sCD27, sCD4, sCD8 and sICAM-1.
de Rie, M. A., Zonneveld, I. M., Witkamp, L., van Lier, R. A., Out, T. A., Bos, J. D.   +5 more
openaire   +4 more sources

Serum TNF-α, sCD8 and sIL-2R levels in childhood tuberculosis

Infection, 1995
In this study we have determined the serum tumor necrosis factor-alpha (TNF-alpha), soluble CD8 (sCD8) and soluble interleukin-2 receptor (sIL-2R) levels in children with active pulmonary tuberculosis (n = 66) and healthy controls (n = 20). Measurable serum TNF-alpha levels were detected in nine of 86 children (10.5%), all of whom belonged to the group
I B, Barlan, M M, Başaran, M, Bakir, F, Tükenmez, N, Bekiroğlu   +4 more
core   +5 more sources