Results 31 to 40 of about 85,967 (221)

sIL-2R- an Immuno-biomarker for Prediction of Metastases in Uveal Melanoma [PDF]

Anticancer Research, 2022
Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. High serum levels of soluble IL-2 receptor (sIL-2R) have been reported in acute inflammations and metastatic cancers. This study evaluated the potential of high/increasing sIL-2R levels in predicting metastases.The study included a total of 1,546 sera samples of subjects ...
Vivian, Barak, Ina, Kalickman, Jacob, Pe'er   +2 more
openaire   +2 more sources

The significance of serum levels of soluble interleukin-2 receptor in patients undergoing maintenance hemodialysis

Renal Failure, 2020
Background Elevated serum levels of sIL-2R are commonly observed in patients undergoing maintenance hemodialysis (MHD). However, the clinical implications in these subjects are unclear.
Xiaohong Chen, Yang Li, Xiaoqiang Ding, Jianzhou Zou, Bo Shen, Zhonghua Liu, Wenlv Lv, Xuesen Cao, Fangfang Xiang   +8 more
doaj   +1 more source

Usefulness of Serum Soluble Interleukin-2 Receptor Levels for Differentiating between PCNSL and SCNSL

Neurologia Medico-Chirurgica, 2023
Serum soluble interleukin-2 receptor (sIL-2R) is a practical tumor marker that is elevated in hematogenous tumors. The purpose of this study was to determine the usefulness of serum sIL-2R for differentiating among malignant brain tumors, including ...
Yuta MITOBE, Ken-ichiro MATSUDA, Yukihiko SONODA   +2 more
doaj   +1 more source

Frequently Relapsing Crohn's Disease Is Characterized by Persistent Elevation in Interleukin-6 and Soluble Interleukin-2 Receptor Serum Levels During Remission [PDF]

, 2000
We examined immune and inflammatory activation during remission in patients with Crohn's disease who presented with various clinical profiles (prolonged remission vs. relapsing disease).
Belaiche, Jacques, Louis, Edouard, Van Kemseke, Catherine   +2 more
core   +1 more source

Clinical value of soluble interleukin-2 receptor in infectious complications. [PDF]

, 1994
In this study, we investigated serum-soluble interleukin-2 receptor (sIL-2r) and neopterin (NPT) levels in five patients with severe postoperative infections. A total of 25 synchronous determinations of sIL-2r and NPT were performed. A marked increase in
Hizuta, Akio, Iwadou, Hironori, Iwagaki, Hiromi, Orita, Kunzo, Perdomo, Jose Antonio, Tanaka, Noriaki   +5 more
core   +1 more source

A new lateral flow assay to detect sIL-2R during T-cell mediated rejection after kidney transplantation [PDF]

, 2021
Kidney is the most frequently transplanted among all solid organs worldwide. Kidney transplant recipients (KTRs) undergo regular follow-up examinations for the early detection of acute rejections. The gold standard for proving a T-cell mediated rejection
Blume, Cornelia, Falk, Christine S., Gwinner, Wilfried, Immenschuh, Stephan, Jonczyk, Rebecca, Kaufeld, Jessica, Lindner, Patrick, Phung, Ncog Linh, Scheffner, Irina, Seiler, Lisa K.   +9 more
core   +2 more sources

Pleural Fluid Soluble Interleukin-2 Receptor as a Biomarker for the Diagnosis of Tuberculosis Pleural Effusion: A Systematic Review and Meta-Analysis

Journal of Tropical Medicine, 2022
Background. Several studies have assessed the diagnostic accuracy of pleural fluid soluble interleukin-2 receptor (sIL-2R) for tuberculous pleural effusion (TPE) but with varied results. Therefore, we conducted this systematic review and meta-analysis to
Zhi Yan, Hua Wang, Wen-Qi Zheng, Zhi-De Hu   +3 more
doaj   +1 more source

Peroxisome Proliferator-Activated Receptor alpha (PPAR alpha) down-regulation in cystic fibrosis lymphocytes [PDF]

, 2006
Background: PPARs exhibit anti-inflammatory capacities and are potential modulators of the inflammatory response. We hypothesized that their expression and/or function may be altered in cystic fibrosis (CF), a disorder characterized by an excessive host ...
A Augarten, A Linden, A Madej, A Trifilieff, AA Ionescu, AE Lovett-Racke, AP Sampson, B Staels, BM Forman, C Andersson, C Hubeau, C Hubeau, DC Jones, E Dagli, F Akbiyik, F McAllister, G Chinetti, H Pall, I Inoue, J Carlstedt-Duke, JD Dignam, JD Tugwood, JH Parmentier, JL Su, JM Shipley, JP Despres, JT Zakrzewski, K Balough, K Beier, KA Kreuzer, LS Nixon, M Ollero, M Roulet, MA Birrell, ME Poynter, N Marx, N Marx, P Delerive, P Greally, P Reineck, PM Farrell, PR Devchand, RB Moss, RB Moss, RB Moss, RU Sorensen, SD Freedman, SM Loitsch, SW Chung, TA Waldmann, TP Dean, TZ Khan, W Wahli, Z Israelian-Konaraki   +53 more
core   +4 more sources

Interleukin-2 Receptor Positive Cells and Circulating Soluble Interleukin-2 Receptors in Patients with Solid Tumors are not Correlated

The International Journal of Biological Markers, 1989
Activated lymphocytes can release a soluble form of IL-2 receptor (sIL-2R), which retains the capacity to bind IL-2. Abnormally high values of sIL-2R have been observed in patients with advanced solid tumors.
P. Lissoni, V. Rizzo, S. Barni, R. Rescaldani, F. Rovelli, A. Biondi, C. Archili, F. Frigerio, G. Tancini   +8 more
doaj   +1 more source

Soluble IL-2 Receptor in Dermatomyositis: Its Associations with Skin Ulcers and Disease Activity

Mediators of Inflammation, 2020
Objective. To investigate the role of soluble interleukin-2R (sIL-2R) in idiopathic inflammatory myopathies (IIM). Methods. Serum sIL-2R levels were measured in 74 dermatomyositis (DM), 16 immune-mediated necrotizing myopathy (IMNM), 24 rheumatoid ...
Linrong He, Xiaoming Shu, Xia Liu, Yongpeng Ge, Sizhao Li, Xin Lu, Guochun Wang   +6 more
doaj   +1 more source