A new lateral flow assay to detect sIL-2R during T-cell mediated rejection after kidney transplantation [PDF]
, 2021 Kidney is the most frequently transplanted among all solid organs worldwide. Kidney transplant recipients (KTRs) undergo regular follow-up examinations for the early detection of acute rejections. The gold standard for proving a T-cell mediated rejection
Blume, Cornelia +9 more
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Circulating soluble tumor necrosis factor receptors, interleukin-2 receptors, tumor necrosis factor-รก, and interleukin-6 levels in rheumatoid arthritis. Longitudinal evaluation during methotrexate and azathioprine therapy [PDF]
, 1993 Contains fulltext : 4749.pdf (publisher's version ) (Open ...
Barrera, P. +8 more
core +6 more sources
Peroxisome Proliferator-Activated Receptor alpha (PPAR alpha) down-regulation in cystic fibrosis lymphocytes [PDF]
, 2006 Background: PPARs exhibit anti-inflammatory capacities and are potential modulators of the inflammatory response. We hypothesized that their expression and/or function may be altered in cystic fibrosis (CF), a disorder characterized by an excessive host ...
C Hubeau +53 more
core +1 more source
Increased angiogenic factor secretion by decidual natural killer cells from pregnancies with high uterine artery resistance alters trophoblast function. [PDF]
, 2014 STUDY QUESTION Are the concentrations of factors secreted by decidual natural killer (dNK) cells from pregnancies at high risk of poor spiral artery remodelling different to those secreted from pregnancies at low risk?
A. E. Wallace +35 more
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Relationship between serum level of interleukin-2 in patients with systemic lupus erythematosus and disease activity in comparison with control group [PDF]
, 2014 Background: Despite the large number of surveys, there are not any validated biomarkers for SLE disease activity till now. This study aimed to evaluate the relationship between serum level of IL-2 in patients with SLE and disease activity in comparison ...
Sedighi, S. +3 more
core +1 more source
Biological significance of soluble IL-2 receptor
Mediators of Inflammation, 1993 A NUMBER of receptors for growth factors and differentiation antigens have been found to be secreted or released by cells. Following mononuclear cell (MNC) activation and interleukin-2 receptor (IL-2R) expression, a soluble form of the Alpha;-chain of IL-
Calogero Caruso +4 more
doaj +1 more source
The International Journal of Biological Markers, 1989 Activated lymphocytes can release a soluble form of IL-2 receptor (sIL-2R), which retains the capacity to bind IL-2. Abnormally high values of sIL-2R have been observed in patients with advanced solid tumors.
P. Lissoni +8 more
doaj +1 more source
Soluble IL-2 Receptor in Dermatomyositis: Its Associations with Skin Ulcers and Disease Activity
Mediators of Inflammation, 2020 Objective. To investigate the role of soluble interleukin-2R (sIL-2R) in idiopathic inflammatory myopathies (IIM). Methods. Serum sIL-2R levels were measured in 74 dermatomyositis (DM), 16 immune-mediated necrotizing myopathy (IMNM), 24 rheumatoid ...
Linrong He +6 more
doaj +1 more source
Journal of Tropical Medicine, 2022 Background. Several studies have assessed the diagnostic accuracy of pleural fluid soluble interleukin-2 receptor (sIL-2R) for tuberculous pleural effusion (TPE) but with varied results. Therefore, we conducted this systematic review and meta-analysis to
Zhi Yan +3 more
doaj +1 more source
EVALUATION OF SERUM SOLUBLE INTERLEUKIN -2 RECEPTOR LEVEL IN DIAGNOSIS OF RHEUMATOID ARTHRITIS
The Iraqi Journal of Medical Sciences, 2016 Background: soluble interleukin-2 receptor (sIL-2R) is secreted by lymphocytes upon activation and has been used as a marker of immune activation in several diseases. Objective: This study aimed to assess the potential clinical utility of serum level of
Eham Amir Ali
doaj +6 more sources