In two patients with primary bone lymphoma (PBL) treated in our clinic, serum levels of soluble interleukin-2 receptor (sIL-2R) reflected the clinical course.
Hiroki Yabe +5 more
doaj +1 more source
Soluble interleukin-2 receptors in ulcerative colitis
T-Cell activation results in the release or shedding of a soluble form (45 kDa) of the cellular (55 kDa) low-affinity interleukin-2 receptor (α-chain) (slL-2R).
O. H. Nielsen, J. Brynskov
doaj +1 more source
Psoriasis is a T-cell-mediated inflammatory skin disease which can be treated successfully with immunosuppressive drugs. Our purpose was to evaluate disease activity of psoriasis and the effect of immunosuppressive treatment by monitoring the soluble T-cell products sIL-2R, sCD27, sCD4, sCD8 and sICAM-1.
de Rie, M. A. +5 more
openaire +3 more sources
Background/Aim The soluble interleukin‐2 receptor (sIL‐2R) serve as a valuable biomarker for tumors in human patients, as its levels increase during the activation of T lymphocytes in clinical states such as inflammation, infection, and tumor. This study
Hyun NamKung +6 more
doaj +1 more source
Applications and Limitations of Inflammatory Biomarkers for Studies on Neurocognitive Impairment in HIV Infection [PDF]
Despite reduced prevalence of severe forms of HIV-associated neurocognitive disorders (HAND) on current antiretroviral therapy (ART) regimens, milder forms of neurocognitive impairment (NCI) remain prevalent in HIV-infected populations.
Cassol, Edana +3 more
core +1 more source
The importance of interleukin-2 and its soluble receptor in patients with multiple sclerosis and other inflammatory diseases of the central nervous system [PDF]
Interleukin-2 (IL-2) was originally identified in 1976 as a growth factor for T lymphocytes. Since that time it has become an important mediator of immune functions through its effects on the growth, development, and activity of T and B lymphocytes ...
Sharief, Mohammad Kassim
core
Low T3 Syndrome in Head-Injured Patients is Associated with Prolonged Suppression of Markers of Cell-Mediated Immune Response [PDF]
Purpose:: To clarify the association between disturbed thyroid hormone metabolism (low T3 syndrome) and release of cytokines and markers of cell-mediated immune response.
Hans*, Volkmar +4 more
core
Cytokines and depression in cancer patients and caregivers. [PDF]
Objective:A better understanding of the biobehavioral mechanisms underlying depression in cancer is required to translate biomarker findings into clinical interventions.
Boutros, Paul C +6 more
core +2 more sources
Early IL-2/sIL-2R surge following surgery leads to temporary immune refractoriness [PDF]
SUMMARYHigh serum level of immunoreactive but not biologically active IL-2 was detected 1 day after surgery in patients undergoing major operation (abdominal, open-heart), in proportion to the tissue injury caused by surgical trauma. IL-2 values were highest in those patients who underwent open-heart surgery and received blood transfusions.
N, Lahat +3 more
openaire +2 more sources
Importance of a Rapid and Accurate Diagnosis in Strongyloides Stercoralis and Human T-Lymphotropic Virus 1 Co-infection: A Case Report and Review of the Literature [PDF]
Strongyloides (S.) stercoralis and Human T-Lymphotropic Virus 1 (HTLV-1) share some endemic regions such as Japan, Jamaica, and South America and are mostly diagnosed elsewhere in immigrants from endemic areas.
Avagnina, Alejandra +7 more
core +2 more sources

