Results 71 to 80 of about 55,581 (203)

Dual Stimuli‐Responsive Polylipoamide Nanoparticles as a Versatile Platform for Efficient pDNA and mRNA Delivery

Small Structures, Volume 7, Issue 6, June 2026.
Stimuli‐responsive polylipoamide nanoparticles are promising in gene delivery owing to their ability to control cargo release within the intracellular environment. This work investigates a comprehensive library of dual pH‐ and reduction‐responsive polylipoamide nanoparticles to understand their structure–property relationships for the design of more ...
Umeka Nayanathara, Shulei Ren, Daniel Yuen, Pengkai Shi, Haikun Liu, Changhe Zhang, Iris Kachel, Yufu Wang, Jacinta F. White, Yuyang Song, Pharvinderjit Kaur, Sahan Samuditha, Fan Yang, Mark Louis P. Vidallon, Angus P. R. Johnston, Xiaowei Wang, Georgina K. Such   +16 more
wiley   +1 more source

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, Volume 13, Issue 5, Page 1078-1083, May 2026.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source

Soluble interleukin-2 receptor is a sensitive diagnostic test in adult HLH

Blood Advances, 2017
: Serum soluble interleukin-2 receptor (sIL-2r) is an important disease marker in hemophagocytic lymphohistiocytosis (HLH), but there are no published data on its diagnostic value in adults.
Anna Hayden, Molly Lin, Sujin Park, Morris Pudek, Marion Schneider, Michael B. Jordan, Andre Mattman, Luke Y.C. Chen   +7 more
doaj   +1 more source

Diffuse Large B‐Cell Lymphoma With Pulmonary and Gastric Involvement Mimicking Nontuberculous Mycobacterial Lung Disease

Respirology Case Reports, Volume 14, Issue 5, May 2026.
An 81‐year‐old man presented with multiple bilateral pulmonary nodules and detection of Mycobacterium intracellulare, initially suggesting nontuberculous mycobacterial lung disease. However, heterogeneous radiological changes and progressive enlargement of selected nodules led to surgical lung biopsy, which revealed diffuse large B‐cell lymphoma with ...
Kosuke Masuda, Kazuhiro Asada, Yuu Saitoh, Makoto Suzuki, Emi Fukasawa, Yumi Fujita, Kosuke Suzuki, Sho Murai, Daisuke Akahori, Mika Saigusa, Taisuke Akamatsu, Akito Yamamoto, Satoru Morita, Toshihiro Shirai   +13 more
wiley   +1 more source

Treatment and outcomes of pulmonary mucosa‐associated lymphoid tissue lymphoma: A multicenter analysis of 186 patients

Cancer, Volume 132, Issue 8, 15 April 2026.
Abstract Background Extranodal marginal zone lymphoma of mucosa‐associated lymphoid tissue (MALT lymphoma) with pulmonary involvement is a rare, indolent lymphoma with no standard treatment approaches. Methods To clarify patient characteristics, treatment, and prognosis of pulmonary MALT lymphoma in the modern era, a multi‐institutional observational ...
Kazutaka Suzuki, Kana Miyazaki, Naoko Asano, Hiroyuki Takahashi, Yusuke Koba, Nobuhiro Hiramoto, Ilseung Choi, Hiroshi Arima, Toshiki Uchida, Nobuhiko Nakamura, Hiro Tatetsu, Hideki Uryu, Shunsuke Ito, Takeharu Kato, Hirokazu Sasaki, Tohru Murayama, Junji Hiraga, Naoki Takahashi, Tetsu Kobayashi, Motoshi Takao, Isao Tawara, Motoko Yamaguchi   +21 more
wiley   +1 more source

Rapidly Progressive Kidney Failure With Transient Non‐Cystic Kidney Enlargement: A Case Report Highlighting Delayed Medullary Cyst Formation

Nephrology, Volume 31, Issue 4, April 2026.
ABSTRACT Hereditary tubulointerstitial kidney diseases typically manifest as slowly progressive chronic kidney disease. Rapidly progressive kidney failure with non‐cystic nephromegaly is an exceptionally rare presentation posing significant diagnostic challenges.
Hiroki Ito, Shigeto Mashiko, Shinichi Mizuno, Yoshitaka Kanomata, Kentaro Yano, Yuya Suzuki, Fumiya Sato, Ryo Tajima, Go Anan, Takuo Hirose, Katsuya Ishiyama, Takefumi Mori   +11 more
wiley   +1 more source

Overall survival based on sIL-2R levels (≤1500 vs. >1500) in DLBCL (A) and FL (B).

, 2013
Serum sIL-2R levels were analyzed in previously untreated patients with DLBCL (n = 104) or FL (n = 30). The 5-year OS rates for patients with sIL-2R levels of ≤1500 U/ml and >1500 U/ml were 76% and 62%, respectively ...
Yoshito Sadahira (483945), Akira Sakai (198243), Hideki Asaoku (483946), Noriaki Yoshida (483937), Masao Seto (73894), Keichiro Mihara (103116), Yuta Katayama (135414), Takashi Nishisaka (483943), Akiro Kimura (483948), Megumu Fujiwara (483942), Naomi Sasaki (483944), Yoshiaki Kuroda (483939), Miyo Oda (483938), Taro Masunari (483941), Yoshiko Okikawa (483940), Koji Arihiro (56456), Hirotaka Matsui (483947)   +16 more
core   +1 more source

Serum Tumor Markers in Non-Hodgkin's Lymphomas and Chronic Lymphocytic Leukemia

The International Journal of Biological Markers, 1993
The levels of soluble interleukin-2 receptors (sIL-2R), beta-2 microglobulin (β-2M), erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were measured in the serum of 50 previously untreated patients with non-Hodgkin's lymphoma (NHL) and ...
A.N. Pavlidis, J. Kalef-Ezra, L.C. Bourantas, A. Lambrou, A. Mavridis   +4 more
doaj   +1 more source

Reliability and Construct Validity of the Physician's Global Assessment of Lung Disease in Systemic Juvenile Idiopathic Arthritis–Associated Lung Disease

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective The physician global assessment of lung disease (PGALD) is a recently proposed disease activity measure for patients with systemic juvenile idiopathic arthritis–associated lung disease (SJIA‐LD). This study evaluates the reliability and construct validity of the PGALD.
Eileen Rife, Guihua Zhai, Mekibib Altaye, Jennifer Andringa, Hermine I. Brunner, Scott Canna, Lauren A. Henderson, Yukiko Kimura, Scott M. Lieberman, Mona Riskalla, Christopher Towe, Tiphanie Vogel, Holly Wobma, Grant Schulert, for the PGALD Validation Consortium Investigators, Rabheh Abdul Aziz, Sheila Angeles‐Han, Kevin Baszis, Edward Behrens, Hermine I. Brunner, Gregory Burg, Scott Canna, Alicia Casey, Matthew Clark, Dominic Co, Kathleen Collins, Randy Cron, Marietta DeGuzman, Fatma Dedeoglu, Robin Deterding, Barbara Eberhard, Deanna Green, Timothy Hahn, Daniel M. Hinds, Patricia Hobday, Sandy Hong, Aimee Hersh, Jennifer Huggins, Yukiko Kimura, Susan Kim, Marisa Klein‐Gitelman, Daniel Lovell, Patricia Lu, Melissa Mannion, Jessica Neely, Michael O'Connor, Karen Onel, Amir Orandi, Andrea Ramirez, Adam Reinhard, Mona Riskalla, Steven Rose, Kristen Ruff, Laisa Santiago, Vivian Saper, Susan Shenoi, Manuel Silva‐Carmona, Emily Smitherman, David R. Spielberg, Jade Tam‐Williams, Christopher Towe, Tracy Ting, Fernando Urrego, Timothy Vece, Tiphanie Vogel, Jennifer Weiss, Holly Wobma, Lauren A. Henderson, Scott M. Lieberman, Julian Vyas, Lisa Young   +70 more
wiley   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source