Results 71 to 80 of about 10,639 (217)

Reliability and Construct Validity of the Physician's Global Assessment of Lung Disease in Systemic Juvenile Idiopathic Arthritis–Associated Lung Disease

open access: yesACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective The physician global assessment of lung disease (PGALD) is a recently proposed disease activity measure for patients with systemic juvenile idiopathic arthritis–associated lung disease (SJIA‐LD). This study evaluates the reliability and construct validity of the PGALD.
Eileen Rife   +70 more
wiley   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang   +7 more
wiley   +1 more source

Reduced‐Dose Bendamustine as a First‐Line Treatment of Follicular Lymphoma Is Associated With Poorer Prognosis

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT The dose of bendamustine used to treat previously untreated follicular lymphoma (FL) is sometimes reduced based on various clinical considerations, but the impact of such dose reductions on outcomes is unclear. We retrospectively analyzed 92 untreated FL patients treated with bendamustine at seven institutions in Japan.
Keisuke Tanaka   +14 more
wiley   +1 more source

The importance of interleukin-2 and its soluble receptor in patients with multiple sclerosis and other inflammatory diseases of the central nervous system [PDF]

open access: yes, 1992
Interleukin-2 (IL-2) was originally identified in 1976 as a growth factor for T lymphocytes. Since that time it has become an important mediator of immune functions through its effects on the growth, development, and activity of T and B lymphocytes ...
Sharief, Mohammad Kassim
core  

Soluble interleukin-2 receptor is a sensitive diagnostic test in adult HLH

open access: yesBlood Advances, 2017
: Serum soluble interleukin-2 receptor (sIL-2r) is an important disease marker in hemophagocytic lymphohistiocytosis (HLH), but there are no published data on its diagnostic value in adults.
Anna Hayden   +7 more
doaj   +1 more source

Primary Diffuse Large B‐Cell Lymphoma Mimicking a Dental Abscess: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin lymphoma, yet its presentation in the maxillofacial region can pose diagnostic challenges, particularly in patients with confounding medical histories. We report the case of a 40‐year‐old Iranian male with a history of ulcerative colitis on mesalazine therapy, who ...
Haniyeh Najafi Aghdam   +2 more
wiley   +1 more source

Understanding the role of P2X7 in affective disorders—are glial cells the major players? [PDF]

open access: yes, 2015
Pathophysiology associated with several psychiatric disorders has been linked to inflammatory biomarkers. This has generated a theory of major depressive disorders as an inflammatory disease.
Jenkins, Trisha A.   +2 more
core   +2 more sources

A case series in patients with enteropathy and granulomatous diseases [PDF]

open access: yes, 2015
Background Although sarcoidosis and celiac disease are both chronic immunologic disorders involving multiple organ systems, reports about association of diseases in individual patients are sparse.
Daum, Severin   +6 more
core   +1 more source

Taming the Cytokine Storm: Therapeutic Strategies for Post‐Acute Sequelae of SARS‐CoV‐2 Infection

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aim Post‐acute sequelae of SARS‐CoV‐2 infection (PASC), commonly referred to as long COVID, has emerged as a significant global health concern, marked by persistent symptoms and chronic inflammation following recovery from acute COVID‐19.
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Serum Tumor Markers in Non-Hodgkin's Lymphomas and Chronic Lymphocytic Leukemia

open access: yesThe International Journal of Biological Markers, 1993
The levels of soluble interleukin-2 receptors (sIL-2R), beta-2 microglobulin (β-2M), erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were measured in the serum of 50 previously untreated patients with non-Hodgkin's lymphoma (NHL) and ...
A.N. Pavlidis   +4 more
doaj   +1 more source

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