Results 61 to 70 of about 10,639 (217)

In vivo evaluation of TNF-alpha in the lungs of patients affected by sarcoidosis [PDF]

, 2015
Introduction. Sarcoidosis is a multisystemic granulomatous disorder characterized by multiple noncaseating granulomas involving intrathoracic lymph nodes and lung parenchyma.
BRUNO, PIERDONATO, GALLI, FILIPPO, LANZOLLA, TIZIANA, Malviya, Gaurav, MARIOTTA, Salvatore, PIETRANGELI, VITTORIO, Ragni, Paola, RICCI, Alberto, SCOPINARO, Francesco, SIGNORE, Alberto   +9 more
core   +5 more sources

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, Volume 13, Issue 5, Page 1078-1083, May 2026.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source

Successful Management of Suspected Epstein–Barr Virus‐Associated Hemophagocytic Lymphohistiocytosis in BRAF‐Mutant Cholangiocarcinoma Following Treatment With Immune Checkpoint Inhibitors and BRAF/MEK Inhibitors: A Case Report [PDF]

Cancer Rep (Hoboken)
ABSTRACT Background The BRAF V600E mutation is a rare genetic alteration in cholangiocarcinoma for which sequential therapy with immune checkpoint inhibitors (ICIs) and BRAF/MEK inhibitors may be effective. However, the full spectrum of adverse events associated with the sequential use of these agents remains unclear. Hemophagocytic lymphohistiocytosis
Shibata A, Ono M, Oiwa S, Uesugi A, Saito S, Usami M, Abe T, Yoshida M, Maeda M, Takada K.   +9 more
europepmc   +2 more sources

Immune activation in prolonged cART-suppressed HIV patients is comparable to that of healthy controls [PDF]

, 2017
Sustained immune activation during chronic HIV infection is considered to augment co-morbidity and mortality. Effective combination antiretroviral therapy (cART) has shown to dampen immune activation especially during the first year cART, but the effects
Boonstra, P.A. (André), Claassen, M.A.A. (Mark), Dries, L.W.J. (Lennert) van den, Gorp, E.C.M. (Eric) van, Groothuismink, Z.M.A. (Zwier)   +4 more
core   +1 more source

Diffuse Large B‐Cell Lymphoma With Pulmonary and Gastric Involvement Mimicking Nontuberculous Mycobacterial Lung Disease

Respirology Case Reports, Volume 14, Issue 5, May 2026.
An 81‐year‐old man presented with multiple bilateral pulmonary nodules and detection of Mycobacterium intracellulare, initially suggesting nontuberculous mycobacterial lung disease. However, heterogeneous radiological changes and progressive enlargement of selected nodules led to surgical lung biopsy, which revealed diffuse large B‐cell lymphoma with ...
Kosuke Masuda, Kazuhiro Asada, Yuu Saitoh, Makoto Suzuki, Emi Fukasawa, Yumi Fujita, Kosuke Suzuki, Sho Murai, Daisuke Akahori, Mika Saigusa, Taisuke Akamatsu, Akito Yamamoto, Satoru Morita, Toshihiro Shirai   +13 more
wiley   +1 more source

Ipilimumab augments antitumor activity of bispecific antibody-armed T cells [PDF]

, 2014
BACKGROUND: Ipilimumab is an antagonistic monoclonal antibody against cytotoxic T-lymphocyte antigen-4 (CTLA-4) that enhances antitumor immunity by inhibiting immunosuppressive activity of regulatory T cells (Treg). In this study, we investigated whether
Abhinav Deol, Archana Thakur, Elyse N Tomaszewski, Hiroshi Yano, Lawrence G Lum, Minsig Choi   +5 more
core   +2 more sources

Treatment and outcomes of pulmonary mucosa‐associated lymphoid tissue lymphoma: A multicenter analysis of 186 patients

Cancer, Volume 132, Issue 8, 15 April 2026.
Abstract Background Extranodal marginal zone lymphoma of mucosa‐associated lymphoid tissue (MALT lymphoma) with pulmonary involvement is a rare, indolent lymphoma with no standard treatment approaches. Methods To clarify patient characteristics, treatment, and prognosis of pulmonary MALT lymphoma in the modern era, a multi‐institutional observational ...
Kazutaka Suzuki, Kana Miyazaki, Naoko Asano, Hiroyuki Takahashi, Yusuke Koba, Nobuhiro Hiramoto, Ilseung Choi, Hiroshi Arima, Toshiki Uchida, Nobuhiko Nakamura, Hiro Tatetsu, Hideki Uryu, Shunsuke Ito, Takeharu Kato, Hirokazu Sasaki, Tohru Murayama, Junji Hiraga, Naoki Takahashi, Tetsu Kobayashi, Motoshi Takao, Isao Tawara, Motoko Yamaguchi   +21 more
wiley   +1 more source

Low T3 Syndrome in Head-Injured Patients is Associated with Prolonged Suppression of Markers of Cell-Mediated Immune Response [PDF]

, 2018
Purpose:: To clarify the association between disturbed thyroid hormone metabolism (low T3 syndrome) and release of cytokines and markers of cell-mediated immune response.
Hans*, Volkmar, Joller-Jemelka, Helen, Kossmann, Thomas, Lenzlinger*, Philipp, Morganti-Kossmann, Maria   +4 more
core  

Rapidly Progressive Kidney Failure With Transient Non‐Cystic Kidney Enlargement: A Case Report Highlighting Delayed Medullary Cyst Formation

Nephrology, Volume 31, Issue 4, April 2026.
ABSTRACT Hereditary tubulointerstitial kidney diseases typically manifest as slowly progressive chronic kidney disease. Rapidly progressive kidney failure with non‐cystic nephromegaly is an exceptionally rare presentation posing significant diagnostic challenges.
Hiroki Ito, Shigeto Mashiko, Shinichi Mizuno, Yoshitaka Kanomata, Kentaro Yano, Yuya Suzuki, Fumiya Sato, Ryo Tajima, Go Anan, Takuo Hirose, Katsuya Ishiyama, Takefumi Mori   +11 more
wiley   +1 more source

18F-FDG PET, genotype-corrected ACE and sIL-2R in newly diagnosed sarcoidosis [PDF]

European Journal of Nuclear Medicine and Molecular Imaging, 2009
Angiotensin-converting enzyme (ACE) and soluble interleukin-2 receptor (sIL-2R) are serological markers, widely used for determining sarcoidosis activity. (18)F-FDG PET has proven to be a sensitive technique in the imaging of sarcoidosis. The aim of this study was to determine sensitivity of (18)F-FDG PET, genotype-corrected ACE and sIL-2R in active ...
Keijsers, R.G., Verzijlbergen, F.J., Oyen, W.J.G., Bosch, J.M. van den, Ruven, H.J., Velzen-Blad, H. van, Grutters, J.C.   +6 more
openaire   +3 more sources