Results 131 to 140 of about 59,140 (257)

Celecoxib in breast cancer prevention and therapy. [PDF]

, 2018
Breast cancer has a high incidence worldwide. The results of substantial studis reveal that inflammation plays an important role in the initiation, development, and aggressiveness of many malignancies. The use of celecoxib, a novel NSAID, is repetitively
Cao, Wei, Hao, Qiongyu, Li, Jieqing, Vadgama, Jaydutt V, Wu, Yong   +4 more
core  

The Survey of Angiogenesis and Myometrial Thickness of Preimplantation Mouse Uterine in Natural Cycle in those Received Human Menopausal Gonadotropin-Human Chorionic Gonadotropin (HMG–HCG) and Sildenafil Citrate

مجله دانشکده پزشکی اصفهان, 2017
Background: Uterus myometrium contractions play crucial role in break or successful embryo implantation. Furthermore, efficient myometrial angiogenesis is important event for supplying endometrium blood.
Gholamreza Dashti, Ariubarzan Farhadi, Mohammad Javad Saeedi-Borujeni, Bahman Rashidi   +3 more
doaj  

Sildenafil effect on testosterone-induced prostate hypertrophy and relaxation of urinary bladder neck muscles

Toxicology Reports
Background: Previous studies have demonstrated the expression of phosphodiesterase-5 receptors in prostate tissue. In this study, we investigated the efficacy of sildenafil citrate in testosterone-induced benign prostate hyperplasia (BPH) in rabbits ...
Qasim A. El-Dwairi, Karem H. Alzoubi, Rania Mahafdeh   +2 more
doaj   +1 more source

PDE5 inhibitors – pharmacology and clinical applications 20 years after sildenafil discovery

British Journal of Pharmacology, 2018
K. Andersson
semanticscholar   +1 more source

Arylthioamides and aryliminothioethers as new slow H2S-releasing agents [PDF]

Hydrogen sulphide (H2S) is emerging as an important endogenous modulator, which exhibits the beneficial effects of nitric oxide (NO) on the cardiovascular (CV) system, without producing toxic metabolites.
ANGELINI, MARIAGRAZIA
core  

Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group.

New England Journal of Medicine, 1998
I. Goldstein, T. Lue, H. Padma-nathan, R. Rosen, W. Steers, P. Wicker   +5 more
semanticscholar   +1 more source

Long-term cardioprotection with phosphodiesterase-5 inhibition against ischemia-reperfusion injury: Role of nitric oxide. [PDF]

, 2005
Recent studies have shown that the potent phosphodiesterase-5 (PDE-5) inhibitor, sildenafil citrate, induces a powerful cardioprotective effect against ischemia-reperfusion (I/R) injury in rabbit and mouse hearts.
Daoud, Vladimir Paul
core   +1 more source

Sildenafil potentiates the antitumor activity of cisplatin by induction of apoptosis and inhibition of proliferation and angiogenesis

Drug Design, Development and Therapy, 2016
Mona Mohamed El-Naa,1 Mohamed Othman,2,3 Sheren Younes4,5 1Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), 6 October City, Egypt; 2Preparatory Year College, University of Hail, Hail, Kingdom of Saudi Arabia; 3Faculty of ...
El-Naa MM, Othman M, Younes S
doaj  

Protective effect of Sildenafil on contralateral epididymal sperm concentration and motility following unilateral blunt testicular trauma in pre-pubertal male mice [PDF]

, 2015
Background and aims: Blunt testicular trauma adversely affects fertility in later periods. The purpose of the present study was to examine the effect of sildenafil on contralateral epididymal sperm count and motility following unilateral blunt testicular
Behfar, Mehdi., Moeini Moghaddam, Reza., Najafi, Gholamreza., Shalizar Jalali, Ali.   +3 more
core  

Use of Sildenafil in Pulmonary Arterial Hypertension: Findings from a U.S. Healthcare Claims Database

Journal of Health Economics and Outcomes Research, 2014
# Background Pulmonary arterial hypertension (PAH) is a disease characterized by dyspnea, fatigue, chest pain and syncope. As there is no known cure for PAH, the goal of treatment is to control symptoms and slow disease progression.
Ariel Berger, John Edelsberg, Simon Teal, Marko A. Mychaskiw, Gerry Oster   +4 more
doaj