Results 111 to 120 of about 400,021 (291)

Epigenetic reprogramming of breast cancer cells with oocyte extracts

Molecular Cancer, 2011
Background Breast cancer is a disease characterised by both genetic and epigenetic alterations. Epigenetic silencing of tumour suppressor genes is an early event in breast carcinogenesis and reversion of gene silencing by epigenetic reprogramming can ...
Kumari Rajendra, Shah Mansi, Sottile Virginie, Dixon James E, Rushton Michael D, Allegrucci Cinzia, Watson Sue, Alberio Ramiro, Johnson Andrew D   +8 more
doaj   +1 more source

PCGF1 Promotes the Tumorigenesis of Malignancies Through Upregulating CCDC34 in Glioma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Polycomb group factor 1 (PCGF1) and coiled‐coil domain‐containing protein 34 (CCDC34) have been implicated in tumorigenesis in multiple malignancies. However, their biological functions and prognostic significance in glioma remain poorly defined.
Yuanbing Chen, Jianbing Xiong, Ziran Ou, Tianhao Zhao, Hui Li, Jun Huang, Zhi Tian, Wuyang Cao   +7 more
wiley   +1 more source

Simultaneous gene silencing and supressing gene silencing in the same cell

, 2013
The present invention relates to genetically modified cells that are capable of optimal transgene expression by co-expressing a silencing suppressor whilst at the same time are also capable of silencing a gene, such as a naturally occurring gene of the ...
Naim, F., Singh, S.P., Wood, C.C.
core  

DNA methylation in follicular lymphoma [PDF]

, 2010
PhDFollicular Lymphoma (FL) is a common B cell Non-Hodgkin Lymphoma with a median survival of 8-10 years. Patients frequently undergo transformation to a more aggressive lymphoma and this is associated with drastically reduced survival.
Ó Riain, Ciarán Liam
core   +2 more sources

Emerging Post‐CMOS Hardware Neurons for Brain‐Inspired Computing: Devices, Circuits, and System Integration

Advanced Functional Materials, EarlyView.
The physical realization of artificial neurons is a critical challenge for energy‐efficient neuromorphic computing. This review presents a comprehensive analysis of the evolution of artificial neuron implementations from conventional CMOS to emerging post‐CMOS technologies.
Kannan Udaya Mohanan, Hocheon Yoo, Benoît H. Lessard, Ioannis Kymissis, Chang‐Hyun Kim   +4 more
wiley   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Suppressor genes as molecular markers of colorectal cancer – a review of the latest reports

, 2020
Suppressor gene research is one of the main current trends in modern cancer research. Oncogenesis, including colorectal cancer (CRC), is a process strictly dependent on the proper functioning of the suppressor genes and their proteins.
Stanisław Głuszek, Agnieszka Piechowska, Monika Wawszczak, Anna Cedro   +3 more
core   +1 more source

Degradable, Skin‐Conformal Nanocomposite‐Based Bioelectronic Patches for High‐Fidelity Electrophysiology and Gesture‐Controlled Robotics

Advanced Functional Materials, EarlyView.
A degradable, skin‐conformal bioelectronic patch combines a starch‐dominated nanocomposite conductor with a gelatin substrate to enable sensitive strain sensing, high‐fidelity electrocardiography, electromyography, electrooculography, and machine‐learning‐assisted gesture control.
Ming Dong, Hongna Yuan, Shubo Liu, Abdulkadir Sanli, Emiliano Bilotti, Han Zhang, Pietro Cataldi, Karin Hing, Oliver Fenwick, Colin J. Humphreys, Dimitrios G. Papageorgiou   +10 more
wiley   +1 more source

Identification of an RNA silencing suppressor encoded by Grapevine leafroll-associated virus 3

, 2012
GLRaV-3, a member of the Closteroviridae family and type member of the genus Ampelovirus, is involved in the grapevine leafroll disease. Until now no RNA silencing suppressor has been found among viruses of this genus, contrary to what happens with a ...
Costa, A., Marques, N T., Gouveia, P., Dandlen, S. A., Nolasco, Gustavo   +4 more
core   +1 more source

The Luteovirus P4 Movement Protein Is a Suppressor of Systemic RNA Silencing [PDF]

, 2017
The plant viral family Luteoviridae is divided into three genera: Luteovirus, Polerovirus and Enamovirus. Without assistance from another virus, members of the family are confined to the cells of the host plant’s vascular system.
Jackson, Craig, Waterhouse, Peter M., Deborah Barton, Kalischuk, Melanie L., Adriana F. Fusaro, Correa, Regis, Corrêa, Régis L., Adriana Fusaro, Regis L. Correa, Barton, Deborah, Lawrence M. Kawchuk, Fusaro, Adriana, Barton, Deborah A., Maite Vaslin, Nakasugi, Kenlee, Deborah A. Barton, Maite F. S. Vaslin, Fusaro, Adriana F., Vaslin, Maite F. S., Lawrence Kawchuk, Melanie L. Kalischuk, Kenlee Nakasugi, Kawchuk, Lawrence, Peter M. Waterhouse, Craig Jackson, Melanie Kalischuk, Kalischuk, Melanie, Peter Waterhouse, Kawchuk, Lawrence M., Regis Correa, Vaslin, Maite   +30 more
core   +1 more source