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The Role of DNA Methylation in Osteosarcoma Pathogenesis and Therapy. [PDF]
Zhou X, Li B, Tao P.
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Viral suppressors of RNA silencing
Current Opinion in Biotechnology, 2001The suppression of RNA silencing by plant viruses represents a viral adaptation to a novel host antiviral defense. Three types of viral suppressors have been identified through the use of a variety of silencing suppression assays. The first two types of suppressor are capable of a complete or partial reversal of pre-existing RNA silencing; the third ...
W X, Li, S W, Ding
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Viral suppressors of RNA silencing
Trends in Plant Science, 2011The infection and replication of viruses in the host induce diverse mechanisms for combating viral infection. One of the best-studied antiviral defence mechanisms is based on RNA silencing. Consistently, several viral suppressors of RNA silencing (VSRs) have been identified from almost all plant virus genera, which are surprisingly diverse within and ...
József, Burgyán, Zoltán, Havelda
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Plant viral suppressors of RNA silencing
Virus Research, 2004RNA silencing is an ancient eukaryotic pathway in which double stranded RNA (dsRNA) triggers destruction of related RNAs in the cell. Early studies in plants pointed to a role for this pathway as a defense against viruses. Most known plant viruses have RNA genomes and replicate via dsRNA intermediates, thereby serving as potent inducers of RNA ...
Braden M, Roth +2 more
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RNA-silencing suppressors of geminiviruses
Journal of General Plant Pathology, 2008Geminiviruses are single-stranded (ss) DNA viruses that not only cause devastating diseases of important food and fiber crops worldwide, but also are important models to study fundamental aspects of virus-induced gene silencing and RNA interference.
Pradeep Sharma, Masato Ikegami
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AtRLI2 is an Endogenous Suppressor of RNA Silencing
Plant Molecular Biology, 2006RNA silencing is a mechanism involved in gene regulation during development and anti-viral defense in plants and animals. Although many viral suppressors of this mechanism have been described up to now, this is not the case for endogenous suppressors.
Cecilia, Sarmiento +4 more
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Sound suppressor silencer baffle
The Journal of the Acoustical Society of America, 2009A baffle for use in a firearm suppressor, which increases the amount of sound and flash that are perceived upon the firing of a firearm upon which a suppressor is placed without substantial alteration to the power or accuracy of the firearm upon which the suppressor is attached.
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RNA Silencing Suppressors: How Viruses Fight Back
Future Virology, 2008RNA silencing is a collective term that refers to diverse RNA-directed processes resulting in sequence-specific degradation of target RNA and repression of gene expression, either at transcriptional or post-transcriptional levels. In animals, fungi and plants, RNA silencing represents a mechanism guided by small RNAs against virus infection.
Yan Shi, Mei Gu, Zaifeng Fan, Yiguo Hong
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Role of Silencing Suppressor Proteins
2008RNA silencing suppressors, developed by plant viruses, are potent arms in the arm race between plant and invading viruses. In higher plants, these proteins efficiently inhibit RNA silencing, which has evolved to defend plants against viral infection in addition to regulation of gene expression for growth and development Virus-encoded RNA-silencing ...
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Characterization of Plant Virus-Encoded Gene Silencing Suppressors
2012Agroinfiltration assay using green fluorescent protein (GFP)-expressing Nicotiana benthamiana line 16c is a powerful method for screening of putative plant virus-encoded gene silencing suppressors. This method allows the investigator to know whether the putative viral suppressor inhibits silencing in a cell (local silencing) and/or spreading of ...
Hajime, Yaegashi +2 more
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