Results 71 to 80 of about 39,412 (269)

Alveolar Epithelial Cell‐Derived Exosomes Regulate Autophagy Through miR‐450b‐5p/HDAC7 to Improve Pulmonary Fibrosis

The FASEB Journal, Volume 39, Issue 20, 31 October 2025.
Alveolar epithelial cell‐derived exosomes (AEC‐Exos) can promote the expression of miR‐450b‐5p in pulmonary fibrotic cells, and miR‐450b‐5p can target and downregulate HDAC7, thereby activating autophagy and alleviating pulmonary fibrosis. ABSTRACT Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease.
Yong Zhou, Zhongkai Tong, Ying Zhou, Yuhan Zhu, Zanbo Chu, Zhaoxing Dong   +5 more
wiley   +1 more source

Endothelial‐Derived CCL7 Promotes Macrophage Polarization and Aggravates Septic Acute Lung Injury via CCR1‐Mediated STAT1 Succinylation

Advanced Science, Volume 12, Issue 38, October 13, 2025.
During sepsis, pulmonary vascular endothelial cells secrete chemokine CCL7, which plays a pivotal role in facilitating the infiltration of C‐C motif chemokine receptor 1‐positive (CCR1+) macrophages into lung tissue. Activation of the CCL7–CCR1 axis enhances the succinylation of STAT1 mediated by KAT2A, thereby driving metabolic reprogramming and ...
Xue Li, Yuqin Long, Yunxi Zhu, Jiahui Gu, Ping Zhou, Changhong Miao   +5 more
wiley   +1 more source

Clinical usefulness of serum angiotensin converting enzyme in silicosis

Pulmonology
Introduction Silicosis is an irreversible and incurable disease. Preventive measures to eliminate exposure are the only effective way to reduce morbidity and mortality.
J. Blanco-Pérez, Á. Salgado-Barreira, S. Blanco-Dorado, M.E. González Bello, A.C. Caldera Díaz, A. Pérez-Gonzalez, A. Pallarés Sanmartín, A. Fernández Villar, F.J. Gonzalez-Barcala   +8 more
doaj   +1 more source

Edukasi Pencegahan Penyakit Paru Akibat Paparan Debu Silika pada Pengrajin Batu Akik di Kota Padang [PDF]

, 2017
Meningkatnya minat masyarakat terhadap batu akik sebagai perhiasan dalam beberapa tahun terakhir di Indonesia mendorong meningkatnya jumlah pengrajin batu akik. Pengrajin batu akik terpapar pada partikel batu yang utamanya terdiri atas silika.
Ilmiawati, C. (Cimi), Reza, M. (Mohamad), Russilawati, R. (Russilawati)   +2 more
core   +2 more sources

The Therapeutic Potential of Andrographolide and Its Derivatives in Inflammatory Diseases

Pharmacology Research &Perspectives, Volume 13, Issue 5, October 2025.
ABSTRACT Andrographolide, a diterpenoid component found in traditional Chinese medicine Andrographis paniculata, is known as a natural antibiotic and can be used to treat inflammatory lesions of various systemic diseases. In recent years, andrographolide derivatives have been continuously synthesized and have shown good anti‐inflammatory ...
Xiaoqin Shan, Siyi Li, Jiayi Liu, Can Wang, Yao Wei, Jiayi Shi, Xinyue Zhang, Lili Gu   +7 more
wiley   +1 more source

CC-chemokine ligand 18, CXC motif chemokine 13 and osteopontin as biomarkers of silicosis and asbestosis: a prospective observational study

Scientific Reports
Background Silicosis and asbestosis, distinct forms of pneumoconiosis, manifest progressive interstitial fibrosis due to exposure to silica dust or asbestos fibers. This study aimed to identify potential biomarkers for diagnosing silicosis and asbestosis,
Na Wu, Changjiang Xue, Shiwen Yu, Yuanying Wang, Di Sun, Qiao Ye   +5 more
doaj   +1 more source

Development of a compact excavator mounted dust suppression system [PDF]

, 2013
This paper reports on the investigation of an excavator mounted dust suppression system for demolition and construction activities. Ever increasing pressure is placed on contractors to improve their environmental performance, especially dust emissions ...
Ahn, Ahn, Arikan, Bartell, Copeland, De Vocht, Dimari, Driussi, Edwards, Gambatese, Gunson, Holman, HSE, HSE, Innovative Technology, Kaveri Ultra Ltd, Kieran Andrew Wallace, Larman, Linnainmaa, Makuch, Mondal, Nij, Petavratzi, Peterson, Pope, Sealpump, Turnkey, Turnkey, Vallero, Wai Ming Cheung, Wessexwater, Wu, Zhao   +32 more
core   +1 more source

m6A Methylation‐Modified hsa_circ_0044226 Attenuates Pulmonary Fibrosis by Suppressing Ferroptosis

Pulmonary Circulation, Volume 15, Issue 4, October 2025.
ABSTRACT Idiopathic Pulmonary fibrosis (IPF) is a debilitating lung condition marked by chronic progression and reduced lung function. This study aimed to explore the functional role and regulatory mechanism of circular RNA circ_0044226 in the pathogenesis of pulmonary fibrosis. The expression of circ_0044226 was analyzed in peripheral blood and TGF‐β1‐
Fei Qi, Liwei Liu, Cheng Peng, Xin Gao, Shanchen Wei, Ming Zhang, Qian Zhou   +6 more
wiley   +1 more source

OC-STAMP is a potential biomarker and therapeutic target for Silicosis: an exploratory investigation

Journal of Translational Medicine
Background Silicosis, a disease characterized by fibrous changes in lung tissue due to prolonged silica dust inhalation, exhibits a complex pathogenesis that remains inadequately addressed by current interventions.
Jing Wu, Bingyu Zhang, Wei Du, Yimin Shi, Chunhong Xie, Yanyan Ke, Xue Yi   +6 more
doaj   +1 more source

Silica and esophageal cancer in Golestan province northeast of Iran [PDF]

, 2007
Objectives: Association of silica with diseases like cancers has been determined previously. This study was designed to determine the quantity of silis in flour produced in Golestan province and its relation to the esophageal cancer. Methodology: We took
Besharat, S., Jabbari, A., Semnani, S.
core