Results 51 to 60 of about 44,667 (255)

The regulatory effect of pulmonary lymphatic drainage on silicosis fibrosis

Ecotoxicology and Environmental Safety, 2022
Silicosis is a fibrotic disease caused by long-term inhalation of SiO2 particles that currently has no effective treatment. Earlier studies have suggested that pulmonary lymphatic vessels play a key role in the transport of silica but have not address ...
Jie Cui, Hailan He, Hong Xu, Ziying Chen, Jingsi Wang, Yi Liu, Xiaohui Hao, Lingli Guo, Heliang Liu, Hongli Wang   +9 more
doaj   +1 more source

Global scenario of silica-associated diseases: A review on emerging pathophysiology of silicosis and potential therapeutic regimes

Toxicology Reports
Silicosis is an occupational fibrotic lung disease caused by exposure to respirable crystalline silica dust particles produced during industrial activities.
Prasad Sherekar, S. Suke, Archana Dhok, Srikant Kashinath Malegaonkar, Shrikrishna A. Dhale   +4 more
semanticscholar   +1 more source

Silicosis, tuberculosis and silica exposure among artisanal and small-scale miners: A systematic review and modelling paper

PLOS Global Public Health, 2023
An estimated 44 million artisanal and small-scale miners (ASM), largely based in developing economies, face significant occupational risks for respiratory diseases which have not been reviewed. We therefore aimed to review studies that describe silicosis
P. Howlett, Hader Mousa, Bibie Said, A. Mbuya, O. Kon, S. Mpagama, J. Feary   +6 more
semanticscholar   +1 more source

Research progress on role of programmed cell death in silicosis and its possible mechanisms

环境与职业医学, 2023
Silicosis is a common occupational disease caused by long-term inhalation of large amounts of free SiO2 dust and deposition in lung tissues, characterized by the formation of silicon nodules and diffuse fibrosis of lung tissues.
Jing WU, Xue YI, Jie WANG
doaj   +1 more source

Lipid characteristics of lung tissue in silicosis rat model were studied based on lipid metabolomics.

Toxicology Letters, 2023
Silicosis is a common occupational disease caused by the long-term inhalation of large amounts of silica dust. Lipid metabolism plays an important role in the progression of silicosis, but its contributing mechanism remains unclear. The aim of this study
Hai-yong He, R. Qi, J. Cui, Mingming Liu, Bo Guan, Yufan Zhou, Yingshu Zhang, X. Hao, Hongli Wang, Heliang Liu   +9 more
semanticscholar   +1 more source

Assessment of NOx Levels in an Underground Hospital Car Park: Implications for Occupational and Environmental Health

Applied Sciences
Environmental air pollution poses a significant threat to human health, with nitrogen oxides (NOx) identified as contributors to respiratory and cardiovascular diseases.
Hector Garcia-Gonzalez, Teresa Lopez-Pola, Daniel Martinez-Gonzalez, Jesus Alonso-Barcena   +3 more
doaj   +1 more source

Effects of mask fitness and worker education on the prevention of occupational dust exposure [PDF]

, 2008
To decrease the incidence of pneumoconiosis, we examined dust protective mask performance and its relation to pulmonary function as well as the effects of worker education on the proper wearing of masks.
Takemura, Yoko, Kishimoto, Takumi, Takigawa, Tomoko, Kojima, Shinji, Wanga, Bing-Ling, Sakano, Noriko, Wang, Da-Hong, Takaki, Jiro, Nishide, Tadashi, Ishikawa, Kou, Ogino, Keiki   +10 more
core   +1 more source

A novel circRNA-SNP may increase susceptibility to silicosis

Ecotoxicology and Environmental Safety, 2022
In this study, we aimed to reveal the association between circRNA-related single nucleotide polymorphisms (SNPs) with the susceptibility of silicosis.
Zhounan Cheng, Yingyi Zhang, Rui Zhao, Yan Zhou, Yang Dong, Anni Qiu, Huiwen Xu, Yiran Liu, Wendi Zhang, Qing Chang, Minjie Chu   +10 more
doaj   +1 more source

Activation of Sirtuin3 by honokiol ameliorates alveolar epithelial cell senescence in experimental silicosis via the cGAS-STING pathway

Redox Biology
Background Silicosis, characterized by interstitial lung inflammation and fibrosis, poses a significant health threat. ATII cells play a crucial role in alveolar epithelial repair and structural integrity maintenance.
Qiang Zhou, Guan Yi, M. Chang, Ning Li, Yichun Bai, Haibin Li, S. Yao   +6 more
semanticscholar   +1 more source

Global and national burden and trends of mortality and disability-adjusted life years for silicosis, from 1990 to 2019: results from the Global Burden of Disease study 2019

BMC Pulmonary Medicine, 2022
Background Silicosis, as an important type of pneumoconiosis, leads to progressive and irreversible conditions from the beginning of inflammation and fibrosis. However, the data on the global burden of silicosis and long-term trends were limited. Methods
Shimin Chen, Miao Liu, F. Xie
semanticscholar   +1 more source