Results 51 to 60 of about 10,531 (157)

A mixed-methods study on impact of silicosis on tuberculosis treatment outcomes and need for TB-silicosis collaborative activities in India

Scientific Reports, 2023
Globally, silicosis and tuberculosis (TB) have been targeted for elimination by 2030. The study’s objectives were to determine the association of silicosis with unfavorable TB treatment outcomes, as well as to explore experts’ perspectives on improving ...
Mihir P. Rupani
doaj   +1 more source

Biogenic Synthesis of Silver and Iron Nanoparticles Derived From Grewia Optiva Leaf Extract: A Novel Approach for Antidiabetic, Anticoagulant and Anti‐Inflammatory Therapies

International Journal of Chemical Kinetics, Volume 58, Issue 4, Page 159-174, April 2026.
ABSTRACT This study presents the green synthesis of silver (Ag‐NPs) and iron nanoparticles (Fe‐NPs) using aqueous leaf extract of Grewia optiva as a natural reducing and stabilizing agent. The extract was prepared using a Kjeldahl apparatus under controlled heating. Nanoparticle synthesis was optimized by varying pH, temperature, and salt concentration,
Muhammad Salman Khan, Khushbakht Asad, Sehrish Asad, Aulia Kanwal, Abdur Rahim, Mina Ziarati, Muhammad Bilal, Nolubabalo Matinise, Farhad Badshah   +8 more
wiley   +1 more source

Systematic Proteomic Characterization of EV‐A71‐Infected Mice Identifies Dynamic Molecular Changes and Therapeutic Targets

MedComm, Volume 7, Issue 4, April 2026.
Time‐resolved multi‐omics of EV‐A71‐infected BALB/c mice uncovered dynamic host responses, revealing rapid neutrophil extracellular traps (NETs) activation as a key event. Screened drugs (kinase inhibitors) suppressed viral replication in vitro and in vivo, suggesting the promise of targeting host phosphorylation networks as a viable antiviral strategy.
Wanjun Peng, Qiaochu Wang, Binbin Zhao, Lihong Zhang, Jing Wu, Xiaohui Wei, Na Rong, Zhaohua Wang, Kaihui Liu, Jiangfeng Liu, Juntao Yang, Jiangning Liu   +11 more
wiley   +1 more source

CC-chemokine ligand 18, CXC motif chemokine 13 and osteopontin as biomarkers of silicosis and asbestosis: a prospective observational study

Scientific Reports
Background Silicosis and asbestosis, distinct forms of pneumoconiosis, manifest progressive interstitial fibrosis due to exposure to silica dust or asbestos fibers. This study aimed to identify potential biomarkers for diagnosing silicosis and asbestosis,
Na Wu, Changjiang Xue, Shiwen Yu, Yuanying Wang, Di Sun, Qiao Ye   +5 more
doaj   +1 more source

Clinical usefulness of serum angiotensin converting enzyme in silicosis

Pulmonology
Introduction Silicosis is an irreversible and incurable disease. Preventive measures to eliminate exposure are the only effective way to reduce morbidity and mortality.
J. Blanco-Pérez, Á. Salgado-Barreira, S. Blanco-Dorado, M.E. González Bello, A.C. Caldera Díaz, A. Pérez-Gonzalez, A. Pallarés Sanmartín, A. Fernández Villar, F.J. Gonzalez-Barcala   +8 more
doaj   +1 more source

Macrophage C3aR1 Mediates Sepsis‐Induced Myocardial Injury by Triggering Neutrophil Necroptosis

Journal of Cellular and Molecular Medicine, Volume 30, Issue 8, April 2026.
ABSTRACT Sepsis‐induced myocardial injury (SIMI) is a leading cause of mortality in critically ill patients, driven by dysregulated immune‐inflammation responses. Although macrophages and neutrophils are key players in this process, the mechanisms governing their crosstalk in SIMI remain unclear. Here, we demonstrate that the complement C3a receptor 1 (
Jianbo Xu, Zhilei He, Rubing Zhang, Chaonan Peng, Ziteng Cai, Xinyue Zhao, Weiqun Wang   +6 more
wiley   +1 more source

Anti‐CD146 Autoantibodies: The First Biologic Markers Associated With Occupational Exposure in Systemic Sclerosis

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective Systemic sclerosis (SSc) is a severe autoimmune disease, with occupational exposure being a significant risk factor. Because CD146 was recently identified as a driver of fibrosis in SSc through regulation of the Wnt/reactive oxygen species interplay, we hypothesized that it is a major autoimmune target in this disease. Methods We developed an
Julien Bermudez, Xavier Heim, Elise Kaspi, Charlotte Reytier, Abdelouahab Beziane, Robin Arcani, Audrey Benyamine, Brigitte Granel, Antoine Villa, Marcel Blot‐Chabaud, Erwan Dumontet, Christophe Paris, Alain Lescoat, Valérie Lecureur, Nathalie Bardin   +14 more
wiley   +1 more source

OC-STAMP is a potential biomarker and therapeutic target for Silicosis: an exploratory investigation

Journal of Translational Medicine
Background Silicosis, a disease characterized by fibrous changes in lung tissue due to prolonged silica dust inhalation, exhibits a complex pathogenesis that remains inadequately addressed by current interventions.
Jing Wu, Bingyu Zhang, Wei Du, Yimin Shi, Chunhong Xie, Yanyan Ke, Xue Yi   +6 more
doaj   +1 more source

Latent tuberculosis infection and infection-associated risk factors for miner workers with silicosis in eastern China

BMC Pulmonary Medicine
Objectives Silicosis people are at high risk of developing pulmonary tuberculosis. Whether silica exposure increases the likelihood of latent tuberculosis infection (LTBI) was not well understood, and potential factors involved in LTBI risk among ...
Xinsong Hu, Cheng Chen, Qianqian Gao, Lang Zhou, Yan Shao, Guoli Li, Honghuan Song, Qiao Liu, Lei Han, Limei Zhu   +9 more
doaj   +1 more source

Silica-exposed patients with silicosis show shorter telomeres than do unexposed individuals: a pilot study in a population in southeastern Brazil [PDF]

Jornal Brasileiro de Pneumologia
Objective: Silicosis is a pneumoconiosis characterized by fibrosis of the lung parenchyma caused by the inhalation of silica particles. Silica dust inhalation is associated with inflammation and induction of oxidative stress in the lungs.
Marcos César Santos de Castro, Lucas de Carvalho Costa, Kaio Cezar Rodrigues Salum, Hermano Albuquerque de Castro, Patrícia Canto Ribeiro, Walter Costa, Angela Santos Ferreira Nani, Fabiana Barzotto Kohlrausch   +7 more
doaj   +1 more source