Results 31 to 40 of about 10,596 (175)
BackgroundSilicosis, a severe lung disease caused by inhaling silica dust, predominantly affects workers in industries such as mining and construction, leading to a significant global public health challenge.
Xinglin Yi +8 more
doaj +1 more source
MSCs exert anti‐inflammatory, anti‐fibrotic and regenerative effects in pulmonary fibrosis. MSC‐derived exosomes reproduce many therapeutic benefits of parental MSCs. Preconditioning and genetic modification improve MSC therapeutic performance. Current preclinical and clinical evidence supports the translational potential of MSC‐based therapies ...
Hajar Nasiri +8 more
wiley +1 more source
Early Identification, Accurate Diagnosis, and Treatment of Silicosis
Silicosis is a global problem, and it has brought about great burdens to society and patients’ families. The etiology of silicosis is clear, preventable, and controllable, but the onset is hidden and the duration is long.
Tian Li +3 more
doaj +1 more source
Silicosis is an occupational respiratory disease caused by inhaling respirable crystalline silica dust. We report the case of silicosis in a 50-year-old woman that presented with pulmonary fibrosis and later developed pulmonary tuberculosis. Her condition is believed to be due to inhalation of dust produced by scrubbing a silica rich surface during ...
Wassef F, Safa, Jose L, Machado
openaire +2 more sources
Metabolic Regulation of Macrophages in Health and Disease
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang +6 more
wiley +1 more source
Allicin Attenuates Silica‐Induced Pulmonary Fibrosis by Targeting the Serpinb2/NF‐κB Pathway
Allicin ameliorates silica‐induced pulmonary fibrosis by suppressing ferroptosis via the Serpinb2/NF‐κB pathway, highlighting its therapeutic potential for silicosis. ABSTRACT Silica‐induced pulmonary fibrosis is a debilitating condition with limited therapeutic options.
Zhou Sijing +6 more
wiley +1 more source
Background The stated intention to eliminate silicosis from the South African goldmining industry as well as current programmes to find and compensate ex-miners with silicosis require an understanding of variation in silicosis prevalence across the ...
Dave Knight +5 more
doaj +1 more source
This case highlights a rare association between usual interstitial pneumonia and celiac disease, broadening the recognized spectrum of pulmonary involvement beyond Lane–Hamilton syndrome. It emphasizes the importance of considering celiac disease in the evaluation of fibrosing interstitial lung disease, particularly when gastrointestinal symptoms are ...
Ragini Gopagoni +6 more
wiley +1 more source
AN UNUSUAL FORM OF SILICOSIS IN A STONE-CUTTER [PDF]
Silicon dioxide or silica is the earth’s most abundant mineral. The primary pulmonary illness attributable to silica exposure is silicosis, which is observed in three forms: classic, accelerated and acute. A case of silicosis is presented in this article
S. A. Sharifian +1 more
doaj +2 more sources
RAB20 deficiency promotes the development of silicosis via NLRP3 inflammasome
Silicosis is a worldwide serious occupational disease that is caused by inhalation of silica crystals. However, little is known about the pathogenesis mechanism of silicosis. We performed single-cell sequencing in bronchoalveolar lavage fluid (BALF) from
Zhouyangfan Peng +4 more
doaj +1 more source

