Multi-omics reveals a novel Cxcr4<sup>+</sup> subpopulation of alveolar macrophages and therapeutic effect of AMD3100 in mice with advanced silicosis. [PDF]
The progression of silicosis‐associated fibrosis relies on a positive feedback loop mediated by crosstalk between Cxcr4+ macrophages and Cxcl12+ fibroblasts and the therapeutic potential of targeting the Cxcl12/Cxcr4 axis with AMD3100 as a novel strategy for treating silicosis.
Mu M +11 more
europepmc +2 more sources
Environmental Impact of Silicic Magmatism in Large Igneous Province Events
Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Scott E. Bryan
wiley +2 more sources
Silicosis, Sarcoidosis, and Silicosarcoidosis Are Overlapping Diagnoses and Difficult to Differentiate. [PDF]
ABSTRACT We evaluated 12 workers with documented exposure to respirable crystalline silica who were referred to a tertiary care center due to clinical suspicion of silicosis, sarcoidosis, or silicosarcoidosis. Although silica exposure is a well‐established risk factor for silicosis and has been associated with autoimmune diseases, mycobacterial ...
Leite GW +9 more
europepmc +2 more sources
Context: Silicosis is a progressive, irreversible and incurable respiratory morbidity and often becomes a cause for pre-mature mortality among occupationally silica dust-exposed workers in India and similar countries.
Subroto S Nandi +2 more
doaj +1 more source
Social determinants of an occupational lung disease: Workers’ narratives on silicosis
Silicosis is a preventable occupational lung disease caused by inhaled silica dust. Solutions to prevent silicosis ranging from engineering controls to respirator use have been validated for nearly a century, but many workers are still at-risk of this ...
Yanni Liang +3 more
doaj +1 more source
Review on role of NLRP3 inflammasome in pathogenesis of silicosis
Silicosis is one of the most common forms of pneumoconiosis globally. Workers who engage in mining, construction, ceramics, and many other industries have a high risk of developing silicosis. Chronic and repeated inhalation of free silica (SiO2) dust (
Zhenzhen FAN +6 more
doaj +1 more source
Asbestosis and silicosis [PDF]
Interstitial fibrosis resulting from workplace exposure to asbestos and crystalline silica persists throughout the world despite knowledge of the causes and effective means for prevention. Asbestosis and silicosis occurrence is predictable among people overexposed to dusts in various industries and occupations such as mining, construction ...
openaire +3 more sources
Moraxella (formerly Branhamella) catarrhalis was discovered at the end of the nineteenth century, and for many decades it was considered to be a harmless commensal of the upper respiratory tract.
Miguel Angel Ariza-Prota +4 more
doaj +1 more source
The regulatory effect of pulmonary lymphatic drainage on silicosis fibrosis
Silicosis is a fibrotic disease caused by long-term inhalation of SiO2 particles that currently has no effective treatment. Earlier studies have suggested that pulmonary lymphatic vessels play a key role in the transport of silica but have not address ...
Jie Cui +9 more
doaj +1 more source
Community-Acquired Pneumonia and Empyema Caused by Citrobacter koseri in an Immunocompetent Patient
Citrobacter species, belonging to the family Enterobacteriaceae, are environmental organisms commonly found in soil, water, and the intestinal tracts of animals and humans.
Miguel Angel Ariza-Prota +4 more
doaj +1 more source

