Results 11 to 20 of about 44,667 (255)
Ecotoxicology and Environmental SafetyBackground: Silicosis is a lethal occupational disease caused by long-term exposure to respirable silica dust. Pulmonary macrophages play a crucial role in mediating the initiation of silicosis.
Hanyujie Kang +4 more
doaj +2 more sources
Frontiers in Public Health, 2023 BackgroundSilicosis, a severe lung disease caused by inhaling silica dust, predominantly affects workers in industries such as mining and construction, leading to a significant global public health challenge.
Xinglin Yi +8 more
doaj +2 more sources
The role of inflammation in silicosis
Frontiers in PharmacologySilicosis is a chronic illness marked by diffuse fibrosis in lung tissue resulting from continuous exposure to SiO2-rich dust in the workplace. The onset and progression of silicosis is a complicated and poorly understood pathological process involving ...
Tong-Tong Liu +4 more
doaj +2 more sources
Scientific Reports, 2023 Globally, silicosis and tuberculosis (TB) have been targeted for elimination by 2030. The study’s objectives were to determine the association of silicosis with unfavorable TB treatment outcomes, as well as to explore experts’ perspectives on improving ...
Mihir P. Rupani
doaj +2 more sources
Archives of Public Health, 2023 Background Differentiated tuberculosis (TB) care is an approach to improve treatment outcomes by tailoring TB management to the particular needs of patient groups based on their risk profile and comorbidities. In silicosis-prone areas, the coexistence of
Mihir P. Rupani
doaj +2 more sources
Early Identification, Accurate Diagnosis, and Treatment of Silicosis
Canadian Respiratory Journal, 2022 Silicosis is a global problem, and it has brought about great burdens to society and patients’ families. The etiology of silicosis is clear, preventable, and controllable, but the onset is hidden and the duration is long.
Tian Li +3 more
doaj +2 more sources
Silicosis, Sarcoidosis, and Silicosarcoidosis Are Overlapping Diagnoses and Difficult to Differentiate. [PDF]
Am J Ind MedABSTRACT We evaluated 12 workers with documented exposure to respirable crystalline silica who were referred to a tertiary care center due to clinical suspicion of silicosis, sarcoidosis, or silicosarcoidosis. Although silica exposure is a well‐established risk factor for silicosis and has been associated with autoimmune diseases, mycobacterial ...
Leite GW +9 more
europepmc +2 more sources
Environmental Impact of Silicic Magmatism in Large Igneous Province Events
Geophysical Monograph Series, Page 133-151., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Scott E. Bryan
wiley +2 more sources
BMC Public Health, 2023 Background Globally, silicosis accounts for 90% of all pneumoconiosis cases and is a serious public health issue. It is characterized by progressive inflammation and irreversible pulmonary fibrosis.
Xin Liu +4 more
semanticscholar +1 more source
Macrophage-Derived Ferritin Exacerbates Silica-Induced Pulmonary Fibrosis via PIK3R2-Mediated Fibroblast Differentiation. [PDF]
Adv Sci (Weinh)This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Wang L +14 more
europepmc +2 more sources