Results 11 to 20 of about 28,331 (250)

The role of inflammation in silicosis

open access: yesFrontiers in Pharmacology
Silicosis is a chronic illness marked by diffuse fibrosis in lung tissue resulting from continuous exposure to SiO2-rich dust in the workplace. The onset and progression of silicosis is a complicated and poorly understood pathological process involving ...
Jian-Dong Jiang, Yun Zhan
exaly   +5 more sources

Silicosis in Switzerland [PDF]

open access: yesInternational Journal of Occupational Medicine and Environmental Health, 2018
The correlation between quartz dust concentrations in the Swiss enterprises and the incidence of silicosis and other related diseases acknowledged as occupational diseases (OD) was investigated.Quartz dust concentrations were obtained from Suva's databases of occupational health surveillance measurements between 2005 and 2014.
Michael F. Koller   +3 more
openaire   +4 more sources

Current status, trends, and predictions in the burden of silicosis in 204 countries and territories from 1990 to 2019

open access: yesFrontiers in Public Health, 2023
BackgroundSilicosis, a severe lung disease caused by inhaling silica dust, predominantly affects workers in industries such as mining and construction, leading to a significant global public health challenge.
Xinglin Yi   +8 more
doaj   +2 more sources

Integrated multi-omics analyses reveal the pro-inflammatory and pro-fibrotic pulmonary macrophage subcluster in silicosis

open access: yesEcotoxicology and Environmental Safety
Background: Silicosis is a lethal occupational disease caused by long-term exposure to respirable silica dust. Pulmonary macrophages play a crucial role in mediating the initiation of silicosis.
Hanyujie Kang   +4 more
doaj   +2 more sources

Tuberculosis and Silicosis: an insightful perspective

open access: yesEgyptian Journal of Chest Disease and Tuberculosis
Tuberculosis (TB) is the most ubiquitous disease related to Silicosis in medium and low-income nations. The government of India has set a target to eliminate TB by 2025, while the International Labor Organization and the WHO aim to eradicate Silicosis ...
Shally Pandit   +4 more
doaj   +2 more sources

Silicosis as a predictor of tuberculosis mortality and treatment failure and need for incorporation in differentiated TB care models in India

open access: yesArchives of Public Health, 2023
Background Differentiated tuberculosis (TB) care is an approach to improve treatment outcomes by tailoring TB management to the particular needs of patient groups based on their risk profile and comorbidities. In silicosis-prone areas, the coexistence of
Mihir P. Rupani
doaj   +2 more sources

Early Identification, Accurate Diagnosis, and Treatment of Silicosis

open access: yesCanadian Respiratory Journal, 2022
Silicosis is a global problem, and it has brought about great burdens to society and patients’ families. The etiology of silicosis is clear, preventable, and controllable, but the onset is hidden and the duration is long.
Tian Li   +3 more
doaj   +2 more sources

Gefitinib and fostamatinib target EGFR and SYK to attenuate silicosis: a multi-omics study with drug exploration

open access: yesSignal Transduction and Targeted Therapy, 2022
Silicosis is the most prevalent and fatal occupational disease with no effective therapeutics, and currently used drugs cannot reverse the disease progress.
Mingyao Wang   +17 more
doaj   +2 more sources

Ac-SDKP modulates apoptosis via HSP27 and the FAS/FASL and mitochondrial axes. [PDF]

open access: yesAnimal Model Exp Med
Schematic diagram of Ac‐SDKP regulating the FAS/FASL and mitochondrial apoptosis pathways via HSP27. Ac‐SDKP inhibits HSP27 expression, activates the FAS/FASL pathway and Caspase‐3 signaling, increases Caspase‐8 and Caspase‐3 expression, and induces cell apoptosis.
Guo W   +13 more
europepmc   +2 more sources

Environmental Impact of Silicic Magmatism in Large Igneous Province Events

open access: yesGeophysical Monograph Series, Page 133-151., 2021

Exploring the links between Large Igneous Provinces and dramatic environmental impact

An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Scott E. Bryan
wiley  

+2 more sources

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