Curcumin Improves Silica Induced Lung Fibrosis by Targeting TLR4-NLRP3 Inflammasome and TGF-β Inhibition in Mice Model. [PDF]
J Biochem Mol ToxicolABSTRACT Silicosis, a progressive occupational lung disease, caused by inhalation of crystalline silica particles, leads to chronic inflammation and pulmonary fibrosis. Increasing evidence suggests that activation of the TLR4/NF‐κB signaling pathway and NLRP3 inflammasome plays a crucial role in silica‐induced lung injury.
Kumari S, Singh P, Dash D, Singh R.
europepmc +2 more sources
Environmental Impact of Silicic Magmatism in Large Igneous Province Events
Geophysical Monograph Series, Page 133-151., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Scott E. Bryan
wiley +2 more sources
Ac-SDKP modulates apoptosis via HSP27 and the FAS/FASL and mitochondrial axes. [PDF]
Animal Model Exp MedSchematic diagram of Ac‐SDKP regulating the FAS/FASL and mitochondrial apoptosis pathways via HSP27. Ac‐SDKP inhibits HSP27 expression, activates the FAS/FASL pathway and Caspase‐3 signaling, increases Caspase‐8 and Caspase‐3 expression, and induces cell apoptosis.
Guo W +13 more
europepmc +2 more sources
Review on role of NLRP3 inflammasome in pathogenesis of silicosis
环境与职业医学, 2022 Silicosis is one of the most common forms of pneumoconiosis globally. Workers who engage in mining, construction, ceramics, and many other industries have a high risk of developing silicosis. Chronic and repeated inhalation of free silica (SiO2) dust (
Zhenzhen FAN +6 more
doaj +1 more source
The regulatory effect of pulmonary lymphatic drainage on silicosis fibrosis
Ecotoxicology and Environmental Safety, 2022 Silicosis is a fibrotic disease caused by long-term inhalation of SiO2 particles that currently has no effective treatment. Earlier studies have suggested that pulmonary lymphatic vessels play a key role in the transport of silica but have not address ...
Jie Cui +9 more
doaj +1 more source
Case Reports in Pulmonology, 2016 Moraxella (formerly Branhamella) catarrhalis was discovered at the end of the nineteenth century, and for many decades it was considered to be a harmless commensal of the upper respiratory tract.
Miguel Angel Ariza-Prota +4 more
doaj +1 more source
Research progress on role of programmed cell death in silicosis and its possible mechanisms
环境与职业医学, 2023 Silicosis is a common occupational disease caused by long-term inhalation of large amounts of free SiO2 dust and deposition in lung tissues, characterized by the formation of silicon nodules and diffuse fibrosis of lung tissues.
Jing WU, Xue YI, Jie WANG
doaj +1 more source
Community-Acquired Pneumonia and Empyema Caused by Citrobacter koseri in an Immunocompetent Patient
Case Reports in Pulmonology, 2015 Citrobacter species, belonging to the family Enterobacteriaceae, are environmental organisms commonly found in soil, water, and the intestinal tracts of animals and humans.
Miguel Angel Ariza-Prota +4 more
doaj +1 more source
Archives of Public Health, 2023 Background Differentiated tuberculosis (TB) care is an approach to improve treatment outcomes by tailoring TB management to the particular needs of patient groups based on their risk profile and comorbidities. In silicosis-prone areas, the coexistence of
Mihir P. Rupani
doaj +1 more source
Analysis of Volatile Organic Compound Emissions in 3D Printing: Implications for Indoor Air Quality
BuildingsThis study provides a comprehensive analysis of volatile organic compound (VOC) emissions in the context of 3D printing, a rapidly advancing technology that is transforming manufacturing processes. As the adoption of 3D printing grows, concerns regarding
Hector Garcia-Gonzalez +3 more
doaj +1 more source