Results 41 to 50 of about 11,574 (132)

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

iMetaMed, Volume 2, Issue 3, September 2026.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo, Yang Zhang, Xin Wang, Shan Cao, Jun Xu   +4 more
wiley   +1 more source

Tuberculosis and Silicosis: an insightful perspective

Egyptian Journal of Chest Disease and Tuberculosis
Tuberculosis (TB) is the most ubiquitous disease related to Silicosis in medium and low-income nations. The government of India has set a target to eliminate TB by 2025, while the International Labor Organization and the WHO aim to eradicate Silicosis ...
Shally Pandit, Sudatta Chandan, Braja S. Barik, Tahziba Hussain, Sanghamitra Pati   +4 more
doaj   +1 more source

Genome-wide mRNA profiling identifies the NRF2-regulated lymphocyte oxidative stress status in patients with silicosis

Journal of Occupational Medicine and Toxicology, 2021
Background The immunomodulatory abnormalities of silicosis are related to the lymphocyte oxidative stress state. The potential effect of antioxidant therapy on silicosis may depend on the variation in nuclear factor erythroid 2-related factor 2 (NRF2 ...
Yingzheng Zhao, Guangcui Xu, Haibin Li, Meiyu Chang, Cheng Xiong, Yingjun Tao, Yi Guan, Yuchun Li, Sanqiao Yao   +8 more
doaj   +1 more source

Atypical Fibrotic‐Mimicking Pulmonary Sarcoidosis in a Young Female: The Basal Conundrum

Respirology Case Reports, Volume 14, Issue 9, September 2026.
We present a case of pulmonary sarcoidosis in a young female who had a confounding basal‐peripheral phenotype, eventually diagnosed through endobronchial biopsy showing non‐necrotizing granulomas with asteroid bodies. ABSTRACT Pulmonary sarcoidosis is a systemic inflammatory disease characterized by the formation of non‐caseating granulomas; it ...
Ali Gohar, Aemin Tariq, Arham Saif, Asma Farooq, Esha Aziz, Muhammad Husnain Ahmad   +5 more
wiley   +1 more source

Novel functional eQTL-SNPs associated with susceptibility to occupational pulmonary fibrosis: A multi-stage study

Ecotoxicology and Environmental Safety
Aim: Identifying the common functional single-nucleotide polymorphisms (SNPs) that can both affect the susceptibility to idiopathic pulmonary fibrosis (IPF) and silicosis.
Rui Zhao, Xiaobo Tao, Wendi Zhang, Siqi Li, Shenxuan Zhou, Anhui Ning, Zhenyu Li, Minjie Chu, Wei Wang, Junhong Jiang   +9 more
doaj   +1 more source

Retinal venular constriction during hypercapnia in highlanders: The potential roles of oxygenation and occupational exposure

Experimental Physiology, EarlyView.
Faisal Ahsaan, Bakhtawar Latif, Aliza Akhtar   +2 more
wiley   +1 more source

Biocompatibility Assessment of Lithium‐Ion Battery Materials in Medical Devices

Small Structures, Volume 7, Issue 9, September 2026.
How safe are lithium‐ion battery materials for medical devices? Antimicrobial performance, cytotoxicity, and biotoxicity are systematically evaluated, and a multidimensional risk‐assessment framework is developed to classify materials from negligible to high risk.
Tingyu Hua, Ming Xu, Zhuofei Jia, Zhiwei Tao, He Yin, Jinzhi Lv, Shanshan Li, Jianan Wang, Wei Yan, Jinhai Wang, Yunlong Zhao   +10 more
wiley   +1 more source

CC-chemokine ligand 18, CXC motif chemokine 13 and osteopontin as biomarkers of silicosis and asbestosis: a prospective observational study

Scientific Reports
Background Silicosis and asbestosis, distinct forms of pneumoconiosis, manifest progressive interstitial fibrosis due to exposure to silica dust or asbestos fibers. This study aimed to identify potential biomarkers for diagnosing silicosis and asbestosis,
Na Wu, Changjiang Xue, Shiwen Yu, Yuanying Wang, Di Sun, Qiao Ye   +5 more
doaj   +1 more source

TRPA1 Regulates Fibrosis‐Associated Transcriptional Pathways in Human Lung Epithelial Cells

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Transient receptor potential ankyrin 1 (TRPA1) is a cation channel originally identified in lung fibroblasts and extensively studied in sensory neurons, where it is associated with pain and neurogenic inflammation. We and others have recently shown that TRPA1 is also expressed in lung epithelial cells and that its expression is regulated by ...
Leevi Halonen, Samu Luostarinen, Ida Valjus, Julia Vistbacka, Antti Pemmari, Eeva Moilanen   +5 more
wiley   +1 more source

Clinical usefulness of serum angiotensin converting enzyme in silicosis

Pulmonology
Introduction Silicosis is an irreversible and incurable disease. Preventive measures to eliminate exposure are the only effective way to reduce morbidity and mortality.
J. Blanco-Pérez, Á. Salgado-Barreira, S. Blanco-Dorado, M.E. González Bello, A.C. Caldera Díaz, A. Pérez-Gonzalez, A. Pallarés Sanmartín, A. Fernández Villar, F.J. Gonzalez-Barcala   +8 more
doaj   +1 more source