Results 31 to 40 of about 13,239 (216)

Multiple effects of silymarin on the hepatitis C virus lifecycle [PDF]

, 2010
Silymarin, an extract from milk thistle (Silybum marianum), and its purified flavonolignans have been recently shown to inhibit hepatitis C virus (HCV) infection, both in vitro and in vivo.
Bourne, Nigel, Brimacombe, Claire L, Cao, Feng, Graf, Tyler N, Grove, Joe, Kane, Olivia J, Lohmann, Volker, Martinez, Laura E, McKeating, Jane A, Nahmias, Yaakov, Negash, Amina, Oberlies, Nicholas H, Owen, David M, Polyak, Stephen J, Pécheur, Eve-Isabelle, Tavis, John E, Wagoner, Jessica   +16 more
core   +1 more source

Evaluation of Liver Damage and Herbal Detoxification of Coral Reef Fish Caused by Ammonia Stress

Aquaculture, Fish and Fisheries, Volume 6, Issue 3, June 2026.
Slybum marianum can reduce ammonia stress and enhance liver protection in marine fish. ABSTRACT Ammonia nitrogen can cause serious toxicological damage to fish and cause fish death. This study focused on liver damage caused by ammonia nitrogen stress in coral reef fish and used herbal extracts to improve ammonia poisoning and prevent liver tissue ...
Wei‐Ting Sun, You‐Ren Lai, De‐Sing Ding, Chih‐Hung Pan   +3 more
wiley   +1 more source

Pachymic Acid Alleviates Non‐Alcoholic Fatty Liver Disease via FGF21‐Mediated Inhibition of the p38 MAPK Pathway

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Pachymic acid alleviates non‐alcoholic fatty liver disease via FGF21‐mediated inhibition of the p38 MAPK pathway. Pachymic acid (PAC) exerts anti‐ non‐alcoholic fatty liver disease (NAFLD) effects by promoting FGF21 expression, activating FGF21/FGFR1 signaling, and thereby suppressing p38 MAPK phosphorylation. ABSTRACT Non‐alcoholic fatty liver disease
Lijuan Nie, Dehong Ma, Xinke Deng, Aga Erbu, Fanli Wang, Wenshuo Shi, Zixuan Li, Huantian Cui, Weibo Wen   +8 more
wiley   +1 more source

Liver Fibrosis: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 5, May 2026.
We systematically summarized the etiologies, diagnostic approaches, and pathogenic mechanisms of liver fibrosis. Also, the therapeutic interventions for liver fibrosis were systematically classified into two main categories: etiological treatment and mechanism‐based antifibrotic therapies.
Jiaorong Qu, Wenqing Qin, Minghang Dong, Zhi Ma, Si Li, Runping Liu, Ranyun Chen, Changmeng Li, Xiaojiaoyang Li   +8 more
wiley   +1 more source

Effect of silver nanoparticles formulated by Silybum marianum on menopausal urinary incontinence in ovariectomized rats

Open Chemistry
Urinary incontinence is the major sign of menopause genitourinary syndrome and is usually related to the sexual dysfunctions. Fifty percent of menopausal women have menopausal urinary tract.
Wei Lingyun, Wang Wenzhen, Feng Na, Qiao Si   +3 more
doaj   +1 more source

Spectral Identification of Disease in Weeds Using Multilayer Perceptron with Automatic Relevance Determination

Sensors, 2018
Microbotryum silybum, a smut fungus, is studied as an agent for the biological control of Silybum marianum (milk thistle) weed. Confirmation of the systemic infection is essential in order to assess the effectiveness of the biological control application
Afroditi Alexandra Tamouridou, Xanthoula Eirini Pantazi, Thomas Alexandridis, Anastasia Lagopodi, Giorgos Kontouris, Dimitrios Moshou   +5 more
doaj   +1 more source

An integrated transcriptome and microbial community analysis reveals potential mechanisms for increased immune responses when replacing silybum marianum meal with soybean meal in growing lambs

Frontiers in Microbiology, 2023
Silybum marianum meal is a by-product that remains silymarin complex and is perceived as a potential-protein source. The potential and its mechanism of silybum marianum meal as a protein supplement in ruminants were evaluated by testing the growth ...
Tianxi Zhang, Tianxi Zhang, Yanbo Ren, Yanbo Ren, Chao Yang, Chao Yang, Kefyalew Gebeyew, Kefyalew Gebeyew, Min Gao, Zhixiong He, Zhixiong He, Zhiliang Tan, Zhiliang Tan   +12 more
doaj   +1 more source

Protective Effect of Silymarin Against Paclitaxel‐Induced Cardiotoxicity

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Paclitaxel, a potent chemotherapeutic agent, induces oxidative stress, inflammation, and apoptosis leading to cardiotoxicity. In this study, silymarin supplementation significantly reduced oxidative stress markers, downregulated inflammatory cytokines (IL‐1β, TNF‐α, NF‐κB), and restored the balance between pro‐ and anti‐apoptotic proteins in rat heart ...
Tuğçe Tutar, Seda Yakut, Adem Kara, Aykut Ulucan, Cüneyt Çağlayan   +4 more
wiley   +1 more source

Antioxidant Activities, Total Flavonoids and Phenolics Content in Different Parts of Silybum Marianum L. Plants

Chemical Engineering Transactions, 2016
Silybum marianum L. is used for the production of silymarin, a flavonoid utilized for regenerating damaged hepatic tissues. Herein, the total flavonoid content (TFC) and total phenolic content (TPC) in the roots, main stems, leaves, fruit receptacles ...
J. Sun, X.H. Li, X.L. Yu
doaj   +1 more source

Occurrence of mycotoxins in milk and dairy products in Brazil: A review of recent data, regulatory aspects, preventive and decontamination strategies

International Journal of Dairy Technology, Volume 79, Issue 2, April–June 2026.
Mycotoxin data in Brazilian milk and dairy products over 20 years indicate aflatoxin M1 as the most frequent, although ochratoxin A, fumonisins and deoxynivalenol were also found in some studies. These data underscore the importance of control measures to reduce dietary mycotoxins in Brazilian dairy feed and avoid their residues in milk.
Sana Ullah, Usama Nasir, Amanda Cristina Dias de Oliveira, Lucas Gabriel Dionisio Freire, Rogério D'Antonio Pires, Karina Nascimento Pereira, Carlos Humberto Corassin, Sher Ali, Carlos Augusto Fernandes de Oliveira   +8 more
wiley   +1 more source