Results 1 to 10 of about 19,240 (226)

Efficient synthesis of aqueous soluble Silymarin nanocrystals from Silybum marianum and assessment of their antibacterial and cytotoxicity insights [PDF]

Scientific Reports
In this paper, aqueous-soluble silymarin nanocrystals (NCs) were prepared using Silybum marianum extract via the solvent evaporation method. The synthesized silymarin NCs were identified by XRD, FESEM/TEM, EDX, FT-IR, and UV–Vis procedures.
Iman Sirvani, Zahra Sabouri, Asma Mostafapour, Majid Darroudi   +3 more
doaj   +2 more sources

Formulation and Characterization of Hydrogel Chitosan–Pectin Active Films Containing Silymarin [PDF]

Molecules
Silymarin—a standardized extract from the seeds of milk thistle (Silybum marianum L. Gaertn.)—is mainly used for the treatment of hepatitis and other liver diseases.
Svetla Dyankova, Nadya Bozakova, Vanya Boneva, Ayten Solak, Veselin Ivanov   +4 more
doaj   +2 more sources

Enhanced Bioavailability and Efficacy of Silymarin Solid Dispersion in Rats with Acetaminophen-Induced Hepatotoxicity

Pharmaceutics, 2021
We evaluated the bioavailability, liver distribution, and efficacy of silymarin-D-α-tocopherol polyethylene glycol 1000 succinate (TPGS) solid dispersion (silymarin-SD) in rats with acetaminophen-induced hepatotoxicity (APAP) compared with silymarin ...
Im-Sook Song, So-Jeong Nam, Ji-Hyeon Jeon, Soo-Jin Park, Min-Koo Choi   +4 more
doaj   +1 more source

Interplay of silymarin and clove fruit extract effectively enhances cadmium stress tolerance in wheat (Triticum aestivum)

Frontiers in Plant Science, 2023
IntroductionOsmoprotectant supplementation can be used as a useful approach to enhance plant stress tolerance. However, the effect of silymarin and clove fruit extract (CFE) on wheat plants grown under cadmium (Cd) stress has not been studied ...
Ahmed H. El-Sappah, Ahmed H. El-Sappah, Mohamed A. S. Metwally, Mostafa M. Rady, Hayssam M. Ali, Linghui Wang, Pulak Maitra, Muhammad Ihtisham, Kuan Yan, Xin Zhao, Jia Li, El-Sayed M. Desoky   +11 more
doaj   +1 more source

Silymarin reduces retinal microvascular damage in streptozotocin-induced diabetic rats

Scientific Reports, 2022
Diabetic retinopathy is a severe microvascular problem in diabetes mellitus. Silymarin is a flavonoid compound, and according to previous studies, it is a bioactive compound with potent antioxidant and anti-inflammatory properties.
Rahman Karimi, Ali Bakhshi, Parisa Dayati, Omid Abazari, Maryamsadat Shahidi, Mohamadreza Savaee, Ehsan Kafi, Mehdi Rahmanian, Seyed Morteza Naghib   +8 more
doaj   +1 more source

Evaluation of silybum marinaum efficacy on University of Wisconsin and histidine-tryptophan-ketoglutarate solutions latter the damage of the perfused liver [PDF]

Acta Cirúrgica Brasileira, 2017
Purpose: To investigate the hepatoprotective and antioxidant effeicacies of Silybum marianum’s (silymarin, S) on University of Wisconsin (UW) and histidinetryptophan-ketoglutarate (HTK) preservation solutions.
Nazmi Özer, Ertan Bülbüloğlu, Serdar Yormaz, İlhan Ece   +3 more
doaj   +2 more sources

Synthesis, characterization and hepatoprotective effect of silymarin phytosome nanoparticles on ethanol-induced hepatotoxicity in rats [PDF]

BioImpacts, 2023
Introduction: Silymarin proved to be a beneficial herbal medicine against many hepatic disorders such as alcoholic liver disease (ALD). However, its application is restricted due to its low bioavailability and consequently decreased efficacy.
Arezoo Gohari Mahmoudabad, Fatemeh Gheybi, Mohsen Mehrabi, Alireza Masoudi, Zeinab Mobasher, Hamid Vahedi, Anneh Mohammad Gharravi, Fatemeh Sadat Bitaraf, Seyed Mahdi Rezayat Sorkhabadi   +8 more
doaj   +1 more source

Evaluating Silymarin Extract as a Potent Antioxidant Supplement in Diazinon-Exposed Rainbow Trout: Oxidative Stress and Biochemical Parameter Analysis

Toxics, 2023
This study aimed to investigate the effects of diazinon on fish, focusing on hepatotoxic biomarkers and the potential protective effects of silymarin supplementation.
Mahdi Banaee, Federica Impellitteri, Cristiana Roberta Multisanti, Antoni Sureda, Francesca Arfuso, Giuseppe Piccione, Caterina Faggio   +6 more
doaj   +1 more source

Effects of Silymarin on Growth Performance, Internal Organs and Some Blood Parameters in Japanese Quail Subjected to Oxidative Stress Induced by Carbon Tetrachloride [PDF]

Poultry Science Journal, 2017
The effects of Silymarin on growth performance, internal organs, and some blood parameters were investigated in Japanese quail that were subjected to oxidative stress induced by carbon tetrachloride (CCl4).
Behboodi HR, Samadi F, Shams Shargh M, Gangi F, Samadi S   +4 more
doaj   +1 more source

Phytosomes as a Plausible Nano-Delivery System for Enhanced Oral Bioavailability and Improved Hepatoprotective Activity of Silymarin

Pharmaceuticals, 2022
Silymarin, a phyto-constituent derived from the plant Silybum marianum, has been widely acknowledged for its hepatoprotective activities. Nevertheless, its clinical utility is adversely hampered by its poor water-solubility and its limited oral ...
Ravi Gundadka Shriram, Afrasim Moin, Hadil Faris Alotaibi, El-Sayed Khafagy, Ahmed Al Saqr, Amr Selim Abu Lila, Rompicherla Narayana Charyulu   +6 more
doaj   +1 more source